apollo
0
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:38 PM IST
Cilago 500mg/500mg Injection is used to treat severe bacterial infections. It contains Cilastatin and Imipenem which work by preventing the formation of the bacterial protective covering, which is necessary for the survival of the bacteria. In some cases, this medicine may cause side effects such as nausea, vomiting, diarrhoea, swelling, and redness at the site of injection. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
Read more
Prescription drug

Whats That

tooltip
Prescription drug
 Trailing icon
Consult Doctor

Manufacturer/Marketer

Gonan Pharma

Consume Type

PARENTERAL

Return Policy

Not Returnable

for this medicine

About Cilago 500mg/500mg Injection

Cilago 500mg/500mg Injection is used to treat severe bacterial infections of the lungs, heart, bladder, skin, kidneys, bones, joints, blood, stomach and female reproductive organs. Cilago 500mg/500mg Injection may also be used in the management of patients with low white blood cell count who have a fever, which is suspected to be due to bacterial infection. Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body. Cilago 500mg/500mg Injection does not work against infections caused by the virus, including cold and flu. 
 
Cilago 500mg/500mg Injection is a combination of two drugs, namely: Cilastatin (dehydropeptidase inhibitor) and Imipenem (antibacterial). Cilastatin inhibits the dehydropeptidase enzyme, which causes the breakdown of Imipenem, thereby helps imipenem to stay active for a longer duration. Imipenem prevents the formation of the bacterial protective covering, which is necessary for the survival of the bacteria. Together, Cilago 500mg/500mg Injection helps to treat bacterial infections.
 
Cilago 500mg/500mg Injection will be administered by a healthcare professional; do not self-administer. In some cases, Cilago 500mg/500mg Injection may cause common side effects such as nausea, vomiting, diarrhoea, swelling, and redness at the site of injection. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor if you are pregnant or breastfeeding. Cilago 500mg/500mg Injection may cause dizziness, so drive with caution. Avoid alcohol consumption as it might cause increased dizziness and sleepiness. Cilago 500mg/500mg Injection should not be given to children below one year or those who weigh below 30kg with kidney problems. Cilago 500mg/500mg Injection is not recommended in paediatric patients with CNS infections due to the risk of seizures. Keep your doctor informed about your health condition and medications to rule out any unpleasant side effects.

Uses of Cilago 500mg/500mg Injection

Treatment of Severe bacterial infections.

Medicinal Benefits

Cilago 500mg/500mg Injection is a combination of two drugs, namely: Cilastatin (dehydropeptidase inhibitor) and Imipenem (antibacterial). Cilago 500mg/500mg Injection is used to treat severe bacterial infections of the lungs, heart, bladder, skin, kidneys, bones, joints, blood, stomach, and female reproductive organs. Cilago 500mg/500mg Injection may also be used in the management of patients with low white blood cell count who have a fever, which is suspected to be due to bacterial infection. Cilastatin inhibits the dehydropeptidase enzyme, which causes the breakdown of Imipenem, thereby helps imipenem to stay active for a longer duration. Imipenem prevents the formation of the bacterial protective covering, which is necessary for the survival of the bacteria. Together, Cilago 500mg/500mg Injection helps to treat bacterial infections. Imipenem is a broad-spectrum antibiotic that is effective against a wide range of aerobic and anaerobic bacteria.

Directions for Use

Cilago 500mg/500mg Injection will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Cilago 500mg/500mg Injection

  • Nausea
  • Vomiting
  • Diarrhoea
  • Swelling
  • Redness at the site of injection

Drug Warnings

Do not take Cilago 500mg/500mg Injection if you are allergic to any of its components. Inform your doctor if you have an allergy to antibiotics, colitis, gastrointestinal disease, urinary/kidney problems, CNS disorders, seizures/fits, or liver problems. Consult your doctor if you are pregnant or breastfeeding. Avoid alcohol consumption as it might cause increased dizziness and sleepiness. Cilago 500mg/500mg Injection should not be given to children below one year or those who weigh below 30kg with kidney problems. Cilago 500mg/500mg Injection is not recommended in paediatric patients with CNS infections due to the risk of seizures. Cilago 500mg/500mg Injection may cause dizziness and sleepiness, so drive with caution.

Drug Interactions

Drug-Drug Interactions: Cilago 500mg/500mg Injection may interact with anti-viral (Ganciclovir), uricosurics (Probenecid), anti-epileptic (Valproic acid, Divalproex sodium), blood thinner (warfarin).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have colitis (inflammation in the lining of the colon), CNS disorders, hemodialysis, kidney or liver dysfunction.

Drug-Drug Interactions Checker List

  • GANCICLOVIR
  • PROBENECID
  • VALPROIC ACID
  • DIVALPROEX SODIUM
  • WARFARIN

Habit Forming

No

Diet & Lifestyle Advise

  • Antibiotics can alter the useful bacteria in the stomach, which help in digestion. Therefore, you are advised to take foods rich in probiotics such as yoghurt/curd, kefir, buttermilk, natto and cheese.
  • Eat fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.
  • Avoid foods rich in calcium, grapefruit and grapefruit juice as they might hinder the absorption of antibiotics.
  • Avoid/limit the consumption of alcohol and usage of tobacco.

Special Advise

  • Cilago 500mg/500mg Injection may cause abnormal Coombs, liver, blood, and kidney function tests. Inform the person doing the tests that you are on treatment with Cilago 500mg/500mg Injection. 

Disease/Condition Glossary

Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect the body. Harmful bacteria produce chemicals known as toxins, which can damage tissue and cause sickness. Symptoms of bacterial infection include fever, chills, and fatigue. Anyone can become infected with a bacterial infection. But, people with a weak immune system or taking immunosuppressive medicines are more prone to bacterial infection.

bannner image

Alcohol

Caution

Avoid alcohol consumption as it might cause increased dizziness and sleepiness.

bannner image

Pregnancy

Caution

Please consult your doctor if you are pregnant or planning for pregnancy. Your doctor will prescribe Cilago 500mg/500mg Injection only if the benefits outweigh the risks.

bannner image

Breast Feeding

Caution

Cilago 500mg/500mg Injection may pass into breast milk. Please consult your doctor if you are breastfeeding; your doctor will decide if Cilago 500mg/500mg Injection can be given to breastfeeding mothers or not.

bannner image

Driving

Caution

Cilago 500mg/500mg Injection may cause dizziness and sleepiness. Avoid driving or operating machinery unless you are alert.

bannner image

Liver

Caution

Dose adjustment may be needed. Please consult your doctor if you have liver impairment/liver disease.

bannner image

Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease.

bannner image

Children

Caution

Cilago 500mg/500mg Injection should not be given to children below one year or those who weigh below 30kg with kidney problems. Cilago 500mg/500mg Injection is not recommended in paediatric patients with CNS infections due to the risk of seizures.

Country of origin

India

Manufacturer/Marketer address

Sector 1, Parwanoo, Himachal Pradesh 173220
Other Info - CI46597

Author Details

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Cilago 500mg/500mg Injection is used to treat severe bacterial infections of the lungs, heart, bladder, skin, kidneys, bones, joints, blood, stomach and female reproductive organs.
Cilago 500mg/500mg Injection is a combination of two drugs, namely: Cilastatin and Imipenem. Cilastatin inhibits the dehydropeptidase enzyme, which causes the breakdown of Imipenem, thereby helps imipenem to stay active for a longer duration. Imipenem prevents the formation of the bacterial protective covering, which is necessary for the survival of the bacteria. Together, Cilago 500mg/500mg Injection helps to treat bacterial infections.
Diarrhoea might be a side-effect of Cilago 500mg/500mg Injection. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience prolonged diarrhoea with abdominal pain, consult your doctor. Do not take anti-diarrheal medicine on your own.
Concomitant administration of Probenecid (used to treat gout and hyperuricemia) along with Cilago 500mg/500mg Injection is not recommended as it might result in an increase of plasma levels and half-life of Imipenem.
Ganciclovir (anti-viral) should not be co-administered along with Cilago 500mg/500mg Injection unless benefits outweigh the risks as generalised seizures have been reported when taken together.
Cilago 500mg/500mg Injection may cause changes in urine colour and amount of urine. Do not worry and consult your doctor if you have any concerns regarding this.
Cilago 500mg/500mg Injection may rarely cause thrush or candidiasis, which is a fungal infection occurring due to the overgrowth of yeast-like fungus in the mouth or throat. Regularly rinse your mouth with water to prevent the growth of fungus.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.