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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:37 PM IST
Aspisol 75 Tablet is an antiplatelet medicine used in the prevention of stroke and heart attack. This combination medicine helps dissolve blood clots, and reduces the risk of blood clot formation, thereby ensuring seamless and free flow of blood. It may cause common side effects like diarrhoea, indigestion, easy bleeding and bruising.
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Prescription drug

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Manufacturer/Marketer

Shreya Life Sciences Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Aspisol 75 Tablet

Aspisol 75 Tablet belongs to the group of antiplatelet agents used for the prevention of stroke and heart attack which occur due to a cessation of blood supply. Heart attack/myocardial infarction is a condition in which the heart does not receive an adequate level of blood supply due to the formation of clots along the way which prevents the free flow of blood. A stroke is an interruption to the blood supply reaching the brain, thereby preventing brain tissue from receiving enough oxygen and nutrients. 

Aspisol 75 Tablet contains ‘’Aspirin and Glycine.’’ Aspirin helps in dissolving clots, which are formed by the clumping together of blood cells called platelets. It helps in reducing the risk of blood clot formation, thereby ensuring seamless and free flow of blood. Glycine, an amino acid helps prevent damage to the stomach lining and acid build-up, thereby lowering the harmful effects of aspirin. Together, Aspisol 75 Tablet helps prevent heart attack and stroke.

Aspisol 75 Tablet is a prescription-only medicine. It may be taken with or without food. Aspisol 75 Tablet should be swallowed whole with a glass of water. Do not crush, chew or break it. In some cases, Aspisol 75 Tablet may cause certain common side effects such as diarrhoea, indigestion, easy bleeding and bruising. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist. 

Keep your doctor informed if you have recently had any surgery. Inform the doctor if you are on antihypertensive, hormonal, anti-diabetes, diuretic, steroid, immunosuppressant, antacid, blood thinner, anti-inflammatory, anti-glaucoma, chemotherapy or mental health therapy. Consult your doctor before taking Aspisol 75 Tablet during pregnancy or if you are breastfeeding. Talk to your doctor before taking alcohol with Aspisol 75 Tablet . Drive with caution as Aspisol 75 Tablet may cause decreased alertness.

Uses of Aspisol 75 Tablet

Prevention of heart attack and stroke

Medicinal Benefits

Aspisol 75 Tablet is a combination drug that works as an anti-platelet and helps in dissolving blood clots, thereby easing the free flow of blood. It hence finds application in disorders that occur due to an interruption of blood supply, like heart attack, stroke and angina. Aspisol 75 Tablet contains Aspirin and Glycine. Aspirin inhibits the cyclooxygenase enzyme (COX enzyme). COX is responsible for catalysing the formation of inflammatory mediators called prostaglandins, and clotting agents called thromboxanes. By inhibiting COX, aspirin suppresses the formation of clotting agents thromboxanes, which would otherwise lead to blood clots. Thereby, aspirin works as a potential blood-thinner, helping blood flow normally and in a fluid manner. Glycine is an essential aminoacid, which has a cardioprotective role. It helps in building the health of cardiac tissue and in enhancing remodelling. It also protects the heart from pressure overload. Thus, Aspisol 75 Tablet finds widespread application in the prevention of heart attack, stroke and angina.

Directions for Use

Take Aspisol 75 Tablet exactly as directed by the physician. Swallow it as a whole with half a glass of water. Do not crush, chew or break it. Aspisol 75 Tablet can be taken with or without food, but it is better to take it with food. The dose and duration will be decided by your doctor based on your need and the severity of the condition.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Aspisol 75 Tablet

  • Nausea
  • Indigestion
  • Diarrhoea
  • Increased tendency for bleeding
  • Feeling sick
  • Hives

Drug Warnings

Do not use Aspisol 75 Tablet if you are allergic to Aspisol 75 Tablet , to NSAID’s or any of the components of Aspisol 75 Tablet . Keep your doctor informed if you suffer from any bleeding disorders, asthma, peptic ulcers, diabetes, hypertension, cardiovascular disorders, kidney disease, liver disease, rheumatoid arthritis, anaemia, menorrhagia, gout, nasal polyps (growths in the nose) and or unusual swellings anywhere in the body. Inform your doctor if you have recently had any surgery. Offer a detailed medical history and inform the doctor if you’ve ever had a heart attack or stroke. Inform the doctor if you are on antihypertensive, hormonal, anti-diabetes, diuretic, steroid, immunosuppressant, antacid, blood thinner, anti-inflammatory, anti-glaucoma, chemotherapy or mental health therapy. Consult your doctor if you are pregnant or breastfeeding. Talk to your doctor before taking alcohol with Aspisol 75 Tablet .

Drug Interactions

Drug-Drug Interactions: Aspisol 75 Tablet may interact with immunosuppressants (ciclosporin, tacrolimus), blood thinners (clopidogrel, warfarin, heparin, phenindione), anticancer drug (methotrexate) and antiviral drugs (ritonavir, lopinavir, atazanavir, darunavir, indinavir), antipsychotics (clozapine), water tablets (furosemide), heart-related medicines (digoxin, amiodarone, verapamil), antimanic drug (lithium), anticonvulsants (valproate, phenytoin), pain killer (ibuprofen), antidiabetic drug (glibenclamide), gout medicine (probenecid), medicines used to treat glaucoma (acetazolamide).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Aspisol 75 Tablet should be used with caution in patients with a known hypersensitivity disorder, angioedema, stomach ulcers, glaucoma, severe kidney problems, liver disease, gout, asthma and uncontrolled diabetes or hypertension. 

Drug-Drug Interactions Checker List

  • CICLOSPORIN
  • TACROLIMUS
  • FUROSEMIDE
  • CLOZAPINE
  • HEPARIN
  • WARFARIN
  • CLOPIDOGREL
  • PHENINDIONE
  • LITHIUM
  • METHOTREXATE
  • INDINAVIR
  • RITONAVIR
  • NELFINAVIR
  • ATAZANAVIR
  • DARUNAVIR
  • DIGITOXIN
  • AMIODARONE
  • VERAPAMIL
  • IBUPROFEN
  • VALPROATE
  • PHENYTOIN
  • GLIBENCLAMIDE
  • PROBENECID
  • ACETAZOLAMIDE

Habit Forming

No

Diet & Lifestyle Advise

  • Reducing weight and having a healthy BMI is very important in enhancing cardiac health.
  • 30 minutes of daily physical exercise can go a long way in preventing heart disease.
  • Avoid smoking to improve cardiac health.
  • Invest in a healthy, balanced diet. Avoid fatty foods, keep your cholesterol in check and load up on the green leafy vegetables, fish, lean meats, nuts and dry fruits. 
  • Reducing stress is very important in keeping a healthy heart. Try yoga and meditation for a relaxed state of mind.

Special Advise

  • Take Aspisol 75 Tablet exactly as prescribed. 
  • In case you miss a dose of Aspisol 75 Tablet , talk to your physician. Never take a double dose. 
  • Do not discontinue taking Aspisol 75 Tablet abruptly or without the advice of the physician.
  • Please know that your doctor may order blood tests to check your hormone levels while you are on Aspisol 75 Tablet . 
  • Your doctor may order a D-dimer to check your clotting profile while on Aspisol 75 Tablet .
  • Your doctor may order liver function tests (LFT’s) and a complete blood picture (CBP) to ascertain the effects of Aspisol 75 Tablet .

Disease/Condition Glossary

Heart Attack: A heart attack (called myocardial infarction) is a serious medical emergency in which blood supply to the heart is interrupted, usually by a blood clot that forms along the way. Symptoms of a heart attack include chest pain, jaw pain, pain on the left side of the body, nausea, dizziness, sweating, a feeling of impending doom etc. 

Stroke: A stroke is an interruption of blood supply to the brain, leading to a lack of oxygen and nutrients received by the brain. A stroke is a medical emergency. Trouble walking, difficulty in understanding speech and in speaking, numbness of the limbs and dizziness are some symptoms of a stroke.

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Alcohol

Unsafe

Avoid taking alcohol with Aspisol 75 Tablet as it may increase the risk of intestinal bleeding. Consult your doctor if you have any concerns.

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Pregnancy

Unsafe

Aspisol 75 Tablet is not recommended for use during pregnancy, especially during the last three months. Consult your doctor if you have any concerns.

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Breast Feeding

Caution

Aspisol 75 Tablet should be used with caution during breastfeeding. Consult your doctor if you have any concerns.

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Driving

Caution

Drive or operate machinery with caution as Aspisol 75 Tablet may cause decreased alertness.

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Liver

Caution

Aspisol 75 Tablet should be used with caution in those with pre-existing liver disease. Please consult your doctor in case of any concerns.

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Kidney

Caution

Aspisol 75 Tablet should be used with utmost caution in those with pre-existing kidney disease. Please consult your doctor in case of any concerns.

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Children

Unsafe

Aspisol 75 Tablet is unsafe to use in children under 12 years of age. Please consult your physician if you have any concerns.

Country of origin

INDIA

Manufacturer/Marketer address

SHREYA HOUSE, 301/A, Pereira Hill Road, Andheri East, Mumbai - 400 099, India
Other Info - ASP0003

Author Details

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FAQs

Aspisol 75 Tablet belongs to the group of antiplatelet agents used for the prevention of stroke and heart attack which occur due to a cessation of blood supply.
Aspisol 75 Tablet works by dissolving blood clots and preventing any cessation of blood supply to the heart or brain.
Aspisol 75 Tablet is not recommended in those suffering from chronic kidney disease. Keep your doctor informed in case of a history of kidney disease.
Aspisol 75 Tablet is very useful in the prevention of a heart attack, in conjunction with other medicines that will be prescribed by your cardiologist. A heart attack is multi-factorial. It is also a medical emergency for which you will need expert prescription and medical care. In case you experience any symptoms of a heart attack, please rush to the hospital.
As warfarin is also a blood thinner, concomitant use with Aspisol 75 Tablet is not recommended as it may lead to bleeding.

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