Apregen 125 mg/80 mg Kit 1's
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Apregen 125 mg/80 mg Kit 1's belongs to a class of drugs called anti-emetics. It is used in combination with other medicines to prevent nausea and vomiting caused by chemotherapy (anti-cancer medicines) in adults and adolescents aged 12 years and above. Nausea is a feeling of uneasiness in the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth.
Apregen 125 mg/80 mg Kit 1's contains Aprepitant, a neurokinin 1 (NK1) receptor antagonist which works by blocking the neurokinin-1 receptor (causes the feeling of sickness) present in the vomiting centre in the brain. Thus, it helps prevent nausea and vomiting.
Take Apregen 125 mg/80 mg Kit 1's as prescribed. You are recommended to take Apregen 125 mg/80 mg Kit 1's for as long as your doctor has advised it. In some cases, Apregen 125 mg/80 mg Kit 1's may cause common side effects such as headache, constipation, loss of appetite, tiredness, indigestion, and hiccups. Most of these side effects do not require medical attention and gradually resolve over time. However, consult your doctor immediately if the side effects persist or worsen.
Please tell your doctor if you are allergic to Apregen 125 mg/80 mg Kit 1's or any other medicines. Apregen 125 mg/80 mg Kit 1's is not recommended for children below 12 years of age. If you are pregnant or breastfeeding, please inform your doctor before taking Apregen 125 mg/80 mg Kit 1's. Avoid driving or operating machinery if you feel dizzy or sleepy after taking Apregen 125 mg/80 mg Kit 1's. If you are taking other prescription or non-prescription medicines, inform your doctor before taking Apregen 125 mg/80 mg Kit 1's.
Apregen 125 mg/80 mg Kit 1's contains Aprepitant, an anti-emetic (a drug used to treat nausea and vomiting) that works by blocking the action of a natural substance in the brain called neurokinin that causes nausea and vomiting. Thus, it is used in combination with other medicines to prevent nausea and vomiting caused by anti-cancer medicines in adults and adolescents from the age of 12 years.
Please tell your doctor if you are allergic to Apregen 125 mg/80 mg Kit 1's or any other medicines. Apregen 125 mg/80 mg Kit 1's is not recommended for children below 12 years of age. If you are pregnant or breastfeeding, please inform your doctor before taking Apregen 125 mg/80 mg Kit 1's. Avoid driving or operating machinery if you feel dizzy or sleepy after taking Apregen 125 mg/80 mg Kit 1's. If you are taking any other prescription or non-prescription medicines, inform your doctor before taking Apregen 125 mg/80 mg Kit 1's.
Drug-Drug Interactions: Avoid taking Apregen 125 mg/80 mg Kit 1's with antipsychotics (pimozide), antiallergic drugs (terfenadine, astemizole), and gastroprokinetic agents (cisapride). Apregen 125 mg/80 mg Kit 1's may interact with immunosuppressants (tacrolimus, everolimus, cyclosporine, sirolimus), pain killers (fentanyl, alfentanil), the medicine used to treat an irregular heartbeat (quinidine), anticancer medicines (etoposide, vinorelbine, irinotecan, ifosfamide), blood thinners (acenocoumarol, warfarin), antibiotics (clarithromycin, telithromycin, rifampicin), anticonvulsants (phenytoin, carbamazepine), medicines used to produce calmness or help you sleep (triazolam, phenobarbital, midazolam), antifungals (ketoconazole, voriconazole, posaconazole, itraconazole), antidepressant (nefazodone), corticosteroids (dexamethasone, methylprednisolone), anti-anxiety medicines (alprazolam), antidiabetic agent (tolbutamide) and medicines used to treat migraines and HIV infections.
Drug-Food Interactions: Apregen 125 mg/80 mg Kit 1's may interact with St. John’s Wort (herbal preparation used to treat depression).
Drug-Disease Interactions: If you have liver disease, inform your doctor before taking Apregen 125 mg/80 mg Kit 1's.
Nausea and vomiting: Nausea is an uneasiness in the stomach that usually precedes vomiting. Vomiting, on the other hand, is a normal bodily response in which a person desires to evacuate stomach contents from the mouth aggressively. In brief, nausea and vomiting are symptoms of a variety of disorders, including infections, motion sickness, an early stage of pregnancy, and gastroparesis (slow stomach emptying). Vomiting is controlled by a receptor in the brain known as the chemoreceptor trigger zone (CTZ). After chemotherapy and radiation therapy, nausea and vomiting are common side effects. It can also arise as a side effect of an operation or surgery. Controlling vomiting and nausea in cancer patients is critical for conducting daily tasks. It can cause mental abnormalities, lack of appetite, malnutrition, and dehydration if not managed.
Alcohol
Consult your doctor
The interaction of alcohol with Apregen 125 mg/80 mg Kit 1's is unknown. If you have any concerns regarding this, please discuss them with your doctor.
Pregnancy
Consult your doctor
If you are pregnant or planning pregnancy, inform your doctor before taking Apregen 125 mg/80 mg Kit 1's. Your doctor may prescribe this medicine only if clearly needed.
Breast Feeding
Consult your doctor
It is unknown whether Aprepitant is excreted in breast milk. Hence, if you are a nursing mother, inform your doctor before taking Apregen 125 mg/80 mg Kit 1's.
Driving
Caution
Apregen 125 mg/80 mg Kit 1's may cause dizziness or drowsiness in some people. Hence, do not drive or operate machinery if you feel dizzy or drowsy after taking Apregen 125 mg/80 mg Kit 1's.
Liver
Caution
If you have liver disease, inform your doctor before taking Apregen 125 mg/80 mg Kit 1's. Your doctor may monitor your liver condition.
Kidney
Consult your doctor
If you have any kidney problems, inform your doctor before taking Apregen 125 mg/80 mg Kit 1's.
Children
Unsafe
Apregen 125 mg/80 mg Kit 1's is not recommended for children below 12 years of age.
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