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Apregen 125 mg/80 mg Kit 1's

Apregen 125 mg/80 mg Kit 1's

Prescription drug
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Composition

APREPITANT-205MG

Manufacturer/Marketer

Cellgen Biopharma

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Apregen 125 mg/80 mg Kit 1's

Apregen 125 mg/80 mg Kit 1's belongs to a class of drugs called anti-emetics. It is used in combination with other medicines to prevent nausea and vomiting caused by chemotherapy (anti-cancer medicines) in adults and adolescents aged 12 years and above. Nausea is a feeling of uneasiness in the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth.

Apregen 125 mg/80 mg Kit 1's contains Aprepitant, a neurokinin 1 (NK1) receptor antagonist which works by blocking the neurokinin-1 receptor (causes the feeling of sickness) present in the vomiting centre in the brain. Thus, it helps prevent nausea and vomiting. 

Take Apregen 125 mg/80 mg Kit 1's as prescribed. You are recommended to take Apregen 125 mg/80 mg Kit 1's for as long as your doctor has advised it. In some cases, Apregen 125 mg/80 mg Kit 1's may cause common side effects such as headache, constipation, loss of appetite, tiredness, indigestion, and hiccups. Most of these side effects do not require medical attention and gradually resolve over time. However, consult your doctor immediately if the side effects persist or worsen. 

Please tell your doctor if you are allergic to Apregen 125 mg/80 mg Kit 1's or any other medicines. Apregen 125 mg/80 mg Kit 1's is not recommended for children below 12 years of age. If you are pregnant or breastfeeding, please inform your doctor before taking Apregen 125 mg/80 mg Kit 1's. Avoid driving or operating machinery if you feel dizzy or sleepy after taking Apregen 125 mg/80 mg Kit 1's. If you are taking other prescription or non-prescription medicines, inform your doctor before taking Apregen 125 mg/80 mg Kit 1's.

Uses of Apregen 125 mg/80 mg Kit 1's

Treatment of Chemotherapy-induced nausea and vomiting

Medicinal Benefits

Apregen 125 mg/80 mg Kit 1's contains Aprepitant, an anti-emetic (a drug used to treat nausea and vomiting) that works by blocking the action of a natural substance in the brain called neurokinin that causes nausea and vomiting. Thus, it is used in combination with other medicines to prevent nausea and vomiting caused by anti-cancer medicines in adults and adolescents from the age of 12 years. 

Directions for Use

Take Apregen 125 mg/80 mg Kit 1's with or without food as advised by your doctor. Always take Apregen 125 mg/80 mg Kit 1's together with other medicines. Swallow it as a whole with some liquid; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Apregen 125 mg/80 mg Kit 1's

  • Headache
  • Constipation
  • Loss of appetite
  • Tiredness
  • Indigestion
  • Hiccups

Drug Warnings

Please tell your doctor if you are allergic to Apregen 125 mg/80 mg Kit 1's or any other medicines. Apregen 125 mg/80 mg Kit 1's is not recommended for children below 12 years of age. If you are pregnant or breastfeeding, please inform your doctor before taking Apregen 125 mg/80 mg Kit 1's. Avoid driving or operating machinery if you feel dizzy or sleepy after taking Apregen 125 mg/80 mg Kit 1's. If you are taking any other prescription or non-prescription medicines, inform your doctor before taking Apregen 125 mg/80 mg Kit 1's.

Drug Interactions

Drug-Drug Interactions: Avoid taking Apregen 125 mg/80 mg Kit 1's with antipsychotics (pimozide), antiallergic drugs (terfenadine, astemizole), and gastroprokinetic agents (cisapride). Apregen 125 mg/80 mg Kit 1's may interact with immunosuppressants (tacrolimus, everolimus, cyclosporine, sirolimus), pain killers (fentanyl, alfentanil), the medicine used to treat an irregular heartbeat (quinidine), anticancer medicines (etoposide, vinorelbine, irinotecan, ifosfamide), blood thinners (acenocoumarol, warfarin), antibiotics (clarithromycin, telithromycin, rifampicin), anticonvulsants (phenytoin, carbamazepine), medicines used to produce calmness or help you sleep (triazolam, phenobarbital, midazolam), antifungals (ketoconazole, voriconazole, posaconazole, itraconazole), antidepressant (nefazodone), corticosteroids (dexamethasone, methylprednisolone), anti-anxiety medicines (alprazolam), antidiabetic agent (tolbutamide) and medicines used to treat migraines and HIV infections.

Drug-Food Interactions: Apregen 125 mg/80 mg Kit 1's may interact with St. John’s Wort (herbal preparation used to treat depression).

Drug-Disease Interactions: If you have liver disease, inform your doctor before taking Apregen 125 mg/80 mg Kit 1's.

Drug-Drug Interactions Checker List

  • PIMOZIDE
  • TERFENADINE
  • ASTEMIZOLE
  • CISAPRIDE
  • TACROLIMUS
  • EVEROLIMUS
  • CYCLOSPORINE
  • SIROLIMUS
  • FENTANYL
  • ALFENTANIL
  • QUINIDINE
  • ETOPOSIDE
  • IRINOTECAN
  • ifosfamide
  • ACENOCOUMAROL
  • WARFARIN
  • CLARITHROMYCIN
  • TELITHROMYCIN
  • RIFAMPICIN
  • PHENYTOIN
  • CARBAMAZEPINE
  • TRIAZOLAM
  • PHENOBARBITAL
  • MIDAZOLAM
  • KETOCONAZOLE
  • VORICONAZOLE
  • POSACONAZOLE
  • ITRACONAZOLE
  • NEFAZODONE
  • DEXAMETHASONE
  • METHYLPREDNISOLONE
  • ALPRAZOLAM
  • TOLBUTAMIDE

Habit Forming

No

Diet & Lifestyle Advise

  • Eat a healthy and low-fat diet that includes lots of fruits and vegetables, lean meats, skinless poultry, nuts, fish, whole grains, and plant-based oils, especially in small portions, as it will be easy for digestion.
  • Avoid eating over-sweet food and include more salty food, especially if you have been vomiting. 
  • Increase the intake of fluids. Drink a small amount of water after small intervals to stay hydrated. 
  • Avoid taking greasy or oily foods, as these foods trigger nausea and vomiting. 
  • If the smell of food makes you feel sick (vomit), do not cook food, as it may worsen your condition. Let someone else do the cooking or use prepared food from the freezer.

Disease/Condition Glossary

Nausea and vomiting: Nausea is an uneasiness in the stomach that usually precedes vomiting. Vomiting, on the other hand, is a normal bodily response in which a person desires to evacuate stomach contents from the mouth aggressively. In brief, nausea and vomiting are symptoms of a variety of disorders, including infections, motion sickness, an early stage of pregnancy, and gastroparesis (slow stomach emptying). Vomiting is controlled by a receptor in the brain known as the chemoreceptor trigger zone (CTZ). After chemotherapy and radiation therapy, nausea and vomiting are common side effects. It can also arise as a side effect of an operation or surgery. Controlling vomiting and nausea in cancer patients is critical for conducting daily tasks. It can cause mental abnormalities, lack of appetite, malnutrition, and dehydration if not managed.

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Alcohol

Consult your doctor

The interaction of alcohol with Apregen 125 mg/80 mg Kit 1's is unknown. If you have any concerns regarding this, please discuss them with your doctor.

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Pregnancy

Consult your doctor

If you are pregnant or planning pregnancy, inform your doctor before taking Apregen 125 mg/80 mg Kit 1's. Your doctor may prescribe this medicine only if clearly needed.

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Breast Feeding

Consult your doctor

It is unknown whether Aprepitant is excreted in breast milk. Hence, if you are a nursing mother, inform your doctor before taking Apregen 125 mg/80 mg Kit 1's.

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Driving

Caution

Apregen 125 mg/80 mg Kit 1's may cause dizziness or drowsiness in some people. Hence, do not drive or operate machinery if you feel dizzy or drowsy after taking Apregen 125 mg/80 mg Kit 1's.

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Liver

Caution

If you have liver disease, inform your doctor before taking Apregen 125 mg/80 mg Kit 1's. Your doctor may monitor your liver condition.

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Kidney

Consult your doctor

If you have any kidney problems, inform your doctor before taking Apregen 125 mg/80 mg Kit 1's.

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Children

Unsafe

Apregen 125 mg/80 mg Kit 1's is not recommended for children below 12 years of age.

Country of origin

India

Manufacturer/Marketer address

Sf-1, Ii-Floor, Rishabh Ipex Mall, Ip Extension, Patparganj, New Delhi- 110092
Other Info - APR0179

Author Details

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FAQs

Apregen 125 mg/80 mg Kit 1's is used to treat Chemotherapy-induced nausea and vomiting.
Apregen 125 mg/80 mg Kit 1's works by blocking the action of a natural substance in the brain called neurokinin that causes nausea and vomiting. Thus, it is used in combination with other medicines to prevent nausea and vomiting caused by anti-cancer medicines in adults and adolescents from the age of 12 years.
You are not recommended to take erythromycin with Apregen 125 mg/80 mg Kit 1's as it may increase the blood levels and effects of Apregen 125 mg/80 mg Kit 1's. Contact your doctor if your condition changes or experience side effects such as diarrhoea, constipation, nausea, or loss of appetite. However, please consult your doctor before taking other medicines with Apregen 125 mg/80 mg Kit 1's.
You are advised not to take hormonal birth control medicines such as birth control pills, implants, skin patches, and certain Intrauterine devices (IUDs) as they may not work properly when taken together with Apregen 125 mg/80 mg Kit 1's. Therefore, you are recommended to use another or additional non-hormonal form of birth control method during treatment with Apregen 125 mg/80 mg Kit 1's and for up to 2 months after using Apregen 125 mg/80 mg Kit 1's.

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