Aplet 60 mg Tablet 60's is an anti-androgen medicine used in the treatment of prostate cancer. Prostate cancer is a form of cancer that begins in the prostate gland cells in men. Symptoms may include difficulty in urinating, pain, numbness, etc. Aplet 60 mg Tablet 60's is used in the treatment of metastatic castration-sensitive prostate cancer and non-metastatic castration-resistant prostate cancer.

Aplet 60 mg Tablet 60's contains Apalutamide, which belongs to the class of androgen inhibitors. It works by inhibiting the production of the testosterone hormone and thus stops the growth and spread of cancer.

Aplet 60 mg Tablet 60's may cause certain side effects such as fatigue, headache, diarrhoea, muscle pain, hot flushes, loss of appetite, and skin rash. These side effects usually subside without any medical attention. Take Aplet 60 mg Tablet 60's as prescribed by your doctor.

Aplet 60 mg Tablet 60's should be avoided if you are allergic to it. Inform your doctor before taking Aplet 60 mg Tablet 60's if you have any pre-existing or a history of liver/kidney disease, cardiovascular diseases like myocardial ischemia, or seizures. Aplet 60 mg Tablet 60's is not recommended for use in children as the safety and efficacy of this medicine are not established. This medicine is only intended for male patients.

Aplet 60 mg Tablet 60's contains Apalutamide, which belongs to the class of androgen inhibitors. Testosterone is a natural hormone produced by the body. This causes an increase in cancer cells in the prostate gland. Aplet 60 mg Tablet 60's works by inhibiting the production of the testosterone hormone and thus stops the growth and spread of cancer. It is mainly intended for use in men only.

• Fatigue
• Headache
• Diarrhoea
• Muscle Weakness
• Hot Flushes
• Loss of Appetite
• Decreased weight
• Increased blood pressure
• Skin rash

Aplet 60 mg Tablet 60's should be avoided if you are allergic to it or any other components present in it. Let your doctor know about your complete medical and medication history beforehand to rule out any side effects. Aplet 60 mg Tablet 60's is not recommended for use in children as the safety and efficacy of this medicine are not established. Aplet 60 mg Tablet 60's may cause cardiovascular and ischemic events, seizures, falls, and fractures in some patients. Hence, inform your doctor if you have/had any conditions like liver/kidney disease, cardiovascular disease, or taking any other medicines before taking Aplet 60 mg Tablet 60's as it may cause serious side effects.

Drug-Drug interactions: Aplet 60 mg Tablet 60's may interact with CYP3A4 substrates (clarithromycin, itraconazole, ketoconazole, verapamil), CYP2C19 substrates (omeprazole, warfarin, diclofenac, phenytoin), CYP2C9 substrates (cyclophosphamide, ibuprofen, trosemide), and some other drugs. 

Drug-Food interactions: No interactions found. 

Drug-Disease interactions: Aplet 60 mg Tablet 60's should be used with caution in patients with severe liver and kidney failure and cardiac problems.

• CLARITHROMYCIN
• VERAMAPIL
• KETOCONAZOLE
• ITRACONAZOLE
• OMEPRAZOLE
• PHENYTOIN
• CYCLOPHOSPHAMIDE
• TORSEMIDE
• DICLOFENAC
• WARFARIN

• Include vegetables like cauliflower, cabbage, broccoli, spinach and kale in your meal. This food slows the growth of prostate cancer and even reduces the risk of prostate cancer.
• It is advised to consume fewer dairy products as these foods may increase the risk of prostate cancer. 
• Physical activity helps strengthen muscles, reduce fatigue, help with weight loss, and give strength.
• Maintain a healthy weight by doing regular simple exercises and yoga. 
• Getting adequate sleep as resting helps improve your health and mental ability and improves attention. 
• Avoid including high amounts of red meat in your diet. When meat is cooked, it may increase the risk of developing prostate cancer.

• Aplet 60 mg Tablet 60's is not recommended for use in female patients and paediatrics.
• Regular monitoring of liver and kidney functioning is recommended, with liver/kidney function tests recommended during Aplet 60 mg Tablet 60's usage.
• Monitor the patients for any signs of cardiovascular conditions while on treatment with Aplet 60 mg Tablet 60's.

Prostate cancer: The prostate gland is a small walnut-sized gland present under the bladder which is responsible for the production of seminal fluid. Prostate cancer is a carcinogenic condition that occurs when the cells of the prostate gland increase out of control. The main cause of this condition is unknown. However, a few underlying reasons that increase the risk for this condition include age, family history, ethnic group, genetic factors, obesity, etc.