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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Jan 1, 2025 | 2:49 PM IST
Antadict 250mg Tablet is used to treat alcohol dependence or chronic alcoholism. It contains Disulfiram, which works by blocking an enzyme that breaks down alcohol in our body. This results in a higher level of acetaldehyde in the blood, causing discomfort and physical reactions. It can help alcohol-addicted people who have decided to quit alcohol drinking by deterring them from drinking again. So, it acts as a supportive agent in the treatment of alcoholism. It may cause common side effects such as drowsiness, tiredness, headache, acne, flushing (warmth, redness, or tingly feeling), sweating, increased thirst, swelling, rapid weight gain, nausea, severe vomiting, neck pain, throbbing headache, blurred vision, fast or pounding heartbeats or fluttering in your chest, confusion, weakness, spinning sensation, feeling unsteady, or and metallic/garlic-like taste in the mouth may occur as your body gets used to the medication. Do not take this medicine if you have consumed alcohol within the past 12 hours.
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Composition :

DISULFIRAM-250MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Antadict 250mg Tablet

Antadict 250mg Tablet is used to treat alcohol dependence or chronic alcoholism. Heavy long-term use of alcohol can cause addiction in an individual, thereby making changes in your brain. Long-term alcohol intake can severely damage your liver and cause liver cirrhosis or fatty liver syndrome.

Antadict 250mg Tablet contains 'Disulfiram', which works by blocking an enzyme that breaks down alcohol in our body. When a patient drinks alcohol, it is changed into acetaldehyde, Antadict 250mg Tablet blocks the enzyme that breaks down acetaldehyde. This results in a higher level of acetaldehyde in the blood, causing discomfort and physical reactions. Antadict 250mg Tablet can help alcohol-addicted people who have decided to quit alcohol drinking by deterring them from drinking again. So, it acts as a supportive agent in the treatment of alcoholism. 

Antadict 250mg Tablet should be taken as prescribed by your doctor, with or without a meal, to avoid stomach upset and at fixed daily intervals for best results. The common side effects of Antadict 250mg Tablet include drowsiness, tiredness, headache, acne, flushing (warmth, redness, or tingly feeling), sweating, increased thirst, swelling, rapid weight gain, nausea, severe vomiting, neck pain, throbbing headache, blurred vision, fast or pounding heartbeats or fluttering in your chest, confusion, weakness, spinning sensation, feeling unsteady, or and metallic/garlic-like taste in the mouth may occur as your body gets used to the medication. Everyone need not experience the above side effects. If the Antadict 250mg Tablet causes any serious case of discomfort, speak with a doctor.

Before starting Antadict 250mg Tablet, do not take Antadict 250mg Tablet if you have consumed alcohol within the past 12 hours. Do not consume alcohol while taking Antadict 250mg Tablet and at least up to 14 days after you stop taking Antadict 250mg Tablet. If your doctor prescribes, Antadict 250mg Tablet is safe to use during pregnancy and breastfeeding. Unpleasant effects may occur after taking minimal amounts of alcohol used in cooking or even if rubbed into the skin. Avoid alcohol-containing aftershaves, perfumes/colognes, body lotions, vinegar, and alcohol-containing mouthwash and hand sanitiser. Even exposure to alcohol-based hand sanitisers in some people can trigger a serious side effect response. Hence, hand washing with water and soap is recommended instead.

Uses of Antadict 250mg Tablet

Treatment of Alcohol addiction

Medicinal Benefits

Antadict 250mg Tablet contains 'Disulfiram', which belongs to 'Antabuse' used to treat alcohol dependence. It works by blocking an enzyme (acetaldehyde) that helps break alcohol in the body. Antadict 250mg Tablet helps alcohol-dependent people who have decided to quit alcohol drinking by deterring them from drinking again.

Side Effects of Antadict 250mg Tablet

  • Drowsiness

  • Tiredness

  • Headache

  • Acne

  • Metallic/garlic-like taste in the mouth

Directions for Use

Swallow Antadict 250mg Tablet as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Before taking the Antadict 250mg Tablet, let your doctor know about all your medical conditions, sensitivities, and all medications you are using. Signs of an overdose of Antadict 250mg Tablet include feeling or being sick, stomach pain, diarrhoea, drowsiness, mental disorders, tiredness, rapid heartbeat, rapid breathing, high body temperature, low blood pressure, loss of muscle control, high blood sugar, changes in the blood (as seen in blood tests). Certain foods, liquid medicines, remedies, tonics, toiletries, perfumes, and sprays may contain enough alcohol to cause a disulfiram tablet-alcohol reaction. So avoid using any alcohol-containing drugs, hand wash, mouth wash or alcoholic beverages as it may lead to an 'aldehyde reaction'.

Therapeutic Class

ANTI-ALCOHOLIC AGENT

Drug-Drug Interactions

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DisulfiramBenznidazole
Critical
DisulfiramParaldehyde
Critical

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • A patient is advised to have a diet that increases serotonin levels which makes a person feel good & involves eating foods high in carbohydrates, especially the complex carbohydrates present in starchy food items like legumes (e.g., beans, lentils and peas), root vegetables (e.g., potatoes and carrots), pasta and bread. Eating such foods in combination with protein in meals will benefit.

  • Deficiencies in B-complex vitamins such as thiamine, folate or folic acid, and B12 are common with alcoholism, and inadequate stores of other B vitamins and vitamin C frequently occur. A patient should take supplements and vitamins on consulting a doctor.

  • Malnutrition is common during alcohol consumption and is revealed slowly and gradually. The patient becomes tired and develops a weaker immune system—which means they are more susceptible to infections. These problems need to be identified and treated during the recovery process—ideally by a team of healthcare professionals.

  • The patient should change his drinking priorities and prefer drinks like apple cider, vanilla shake, mixing juice or lemonade with sparkling water etc.

Habit Forming

No

How Antadict 250mg Tablet Works

Antadict 250mg Tablet contains 'Disulfiram', which works by blocking an enzyme that breaks down alcohol in our body. When a patient drinks alcohol, it is changed into acetaldehyde, Antadict 250mg Tablet blocks the enzyme that breaks down acetaldehyde. This results in a higher level of acetaldehyde in the blood, causing discomfort and physical reactions. Antadict 250mg Tablet can help alcohol-addicted people who have decided to quit alcohol drinking by deterring them from drinking again. So, it acts as a supportive agent in the treatment of alcoholism.

What if I have taken an overdose of Antadict 250mg Tablet

Do not take more than the prescribed dose of Antadict 250mg Tablet as it may cause overdose. The symptoms of overdose include drowsiness, vomiting, loss of consciousness or loss of coordination. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.
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Alcohol

Unsafe

Not recommended for alcoholism as Antadict 250mg Tablet and alcohol causes severe 'aldehyde reaction' causing life-threatening conditions.

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Pregnancy

Caution

Not enough data available but Antadict 250mg Tablet is not given in pregnant females unless recommended in a doctor.

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Breast Feeding

Unsafe

Not recommended as such, as not enough data is available. Breastfeeding mothers should consult a doctor before taking the Antadict 250mg Tablet.

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Driving

Caution

Not recommended before driving. Antadict 250mg Tablet has been found to cause drowsiness in the patient. Hence, taking Antadict 250mg Tablet before driving or performing hazardous tasks is not recommended.

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Liver

Caution

Not recommended in liver patients. Antadict 250mg Tablet has been found to cause liver damage in patients & hence not recommended to be taken without doctors consultation.

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Kidney

Caution

Not recommended in kidney patients. Antadict 250mg Tablet should be taken by kidney patients only on doctors consultation.

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Children

Unsafe

Strictly not recommended in children. it may result in neurological interactions resulting in harmful symptoms.

Country of origin

India
Other Info - AN90794

Author Details

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FAQs

Antadict 250mg Tablet is used to treat alcohol dependence or chronic alcoholism.
Antadict 250mg Tablet contains 'Disulfiram', which belongs to 'Antabuse' used to treat alcohol dependence. It works by blocking an enzyme (acetaldehyde) that helps break alcohol in the body. Antadict 250mg Tablet helps alcohol-dependent people who have decided to quit alcohol drinking by deterring them from drinking again.
An asthmatic patient, if already on cough-suppressing medications like diphenhydramine, is not recommended to take Antadict 250mg Tablet. Antadict 250mg Tablet and diphenhydramine are contraindicated and may result in harmful implications.
Not recommended in patients taking blood thinners like warfarin to prevent blood clot formation inside heart/brain vessels. Warfarin (blood thinner) and Antadict 250mg Tablet are contraindicated and should not be taken together.
Yes, Antadict 250mg Tablet has been implicated in altering the results of tests done for adrenal tumours & hence not recommended to be taken before any diagnostic test is done.
The common side effects of Antadict 250mg Tablet are usually temporary, including headaches, nausea, a metallic taste in the mouth and feeling tired.
Take the missed dose as soon as you remember. Take the rest of the day's doses at evenly spaced intervals unless otherwise directed by your doctor.
Antadict 250mg Tablet is safe if taken in the dose and duration prescribed by the doctor.
Antadict 250mg Tablet is not an over-the-counter medicine. It can be taken only when prescribed by the doctor.
Antadict 250mg Tablet is not addictive. It does not have habit-forming tendencies.
Antadict 250mg Tablet will not work for everyone. It is used to help people with an alcohol addiction who have already stopped drinking and are maintaining their ability to no longer drink alcohol. Antadict 250mg Tablet is not recommended for people with heart failure or coronary artery disease.
Antadict 250mg Tablet does not stop cravings. It is a medicine used along with social support and counselling, to help people recover from alcohol use disorder and to avoid having the urge to drink alcohol again. It causes sudden, undesirable effects when mixed with alcohol to help you refrain from alcohol, even if you are dependent on alcohol.
Antadict 250mg Tablet takes 1-2 hours to start working. For the full benefits, keep taking Antadict 250mg Tablet for the prescribed duration.

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