Ancef XP 281.25mg Injection belongs to the group of antibiotics called 'cephalosporin' used to treat various bacterial infections of the nose, lungs, ear, bones, joints, skin, urinary tract, prostate gland and reproductive system. Besides this, Ancef XP 281.25mg Injection also used before surgeries to prevent post-surgical bacterial infections. Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body. Infectious or harmful bacteria can make you sick and reproduce quickly in your body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. Ancef XP 281.25mg Injection does not work against infections caused by the virus, including cold and flu.

Ancef XP 281.25mg Injection contains 'Cefazolin' works by interfering with the formation of bacterial cell walls, thereby impairing the bonds that hold the bacterial cell wall together. This allows holes to appear in the bacterial cell walls, which kills the bacteria. Thus, it helps in treating and preventing the spread of infections.

You are advised to take Ancef XP 281.25mg Injection for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience injection site reactions (pain, swelling, redness), vomiting, allergic reaction, nausea, indigestion, diarrhoea, lightheadedness and dizziness. Most of these side effects of Ancef XP 281.25mg Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Some patients may experience ‘Clostridium difficile associated diarrhoea (CDAD)’ a condition in which healthy bacteria in the colon (intestine) are disrupted.

If you are allergic to Ancef XP 281.25mg Injection, penicillins or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before taking Ancef XP 281.25mg Injection. Drive only if you are alert as Ancef XP 281.25mg Injection may cause dizziness. You are recommended to complete the full course of Ancef XP 281.25mg Injection as prescribed by your doctor for effective results. Please do not take Ancef XP 281.25mg Injection on your own as self-medication may lead to antibiotic-resistance in which antibiotics fail to act against specific bacterial infections. 

Ancef XP 281.25mg Injection belongs to the group of antibiotic medicines called cephalosporins used to treat various bacterial infections of the brain, lungs, middle ear, abdomen, urinary tract, kidneys, bones, joints, skin, soft tissues, blood, heart, chest, lime disease (caused by tick bites), and gonorrhoea (sexually transmitted disease).  It is also used before surgeries to prevent post-surgical bacterial infections. Ancef XP 281.25mg Injection contains Cefazolin is a broad-spectrum antibiotic that is effective against gram-positive and gram-negative bacteria, aerobic and some anaerobic bacteria.  Ancef XP 281.25mg Injection works by preventing the formation of bacterial cell covering, which is necessary for their survival. Thereby, kills the bacteria and helps in treating and preventing the spread of infections.

• Injection site reactions (pain, swelling, redness)
• Nausea
• Vomiting
• Allergic reaction
• Indigestion
• Diarrhoea
• Lightheadedness
• Dizziness

If you are allergic to Ancef XP 281.25mg Injection, penicillins or any other medicines, please tell your doctor. If you have kidney or liver problems, diarrhoea, haemolytic anaemia (reduction in red blood cells that may make your skin pale yellow and cause breathlessness or weakness), kidney or gall stones, inflammation of the large intestine, inform your doctor before taking Ancef XP 281.25mg Injection. Do not take Ancef XP 281.25mg Injection on your own as self-medication may lead to antibiotic-resistance in which antibiotics fail to act against specific bacterial infections. Do not take antacids and calcium-containing products along with Ancef XP 281.25mg Injection; maintain a gap of 2-3 hours between both. If you are pregnant or breastfeeding, please inform your doctor before taking Ancef XP 281.25mg Injection. Use Ancef XP 281.25mg Injection with extreme caution in elderly patients above 65 years of age as there is an increased risk of severe adverse effects. You are recommended to complete the full course of Ancef XP 281.25mg Injection as prescribed by your doctor for effective results. Drive only if you are alert as Ancef XP 281.25mg Injection may cause dizziness. Avoid alcohol consumption while taking Ancef XP 281.25mg Injection to prevent unpleasant side-effects. Inform your doctor about all the medicines you are taking and about your health condition to rule out any undesirable side-effects. 

Drug-Drug Interaction: Ancef XP 281.25mg Injection may interact with a blood thinner (warfarin, heparin), drugs used to lower high uric acid levels (probenecid), water pills or diuretics (furosemide, bumetanide), antibiotics (chloramphenicol, gentamicin, streptomycin, neomycin, tobramycin), vaccine (BCG, cholera, typhoid).

Drug-Food Interaction: Ancef XP 281.25mg Injection may interact with alcohol. Therefore, avoid the consumption of alcohol with Ancef XP 281.25mg Injection as it may increase the risk of adverse effects.

Drug-Disease Interaction: If you have kidney or liver problems, diarrhoea, haemolytic anaemia (reduction in red blood cells that may cause breathlessness or weakness and make your skin pale yellow), kidney or gall stones, inflammation of the large intestine and liver disease, inform your doctor before taking Ancef XP 281.25mg Injection.

• WARFARIN
• HEPARIN
• PROBENECID
• FUROSEMIDE
• BUMETANIDE
• CHLORAMPHENICOL
• GENTAMICIN
• NEOMYCIN
• TOBRAMYCIN
• STREPTOMYCIN
• BACILLUS CALMETTE-GUERIN(BCG) VACCINE
• CHOLERA VACCINE
• TYPHOID VACCINE

• Take probiotics after completing the full course of Ancef XP 281.25mg Injection to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like cheese, yoghurt, kombucha, sauerkraut and kimchi can restore the good bacteria of the intestine.
• Include fibre-rich foods, as they can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fibre-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains such as whole-grain bread, brown rice should be included in your diet.
• Make sure you drink plenty of water or other fluids every day while you are taking Ancef XP 281.25mg Injection.
• Avoid foods rich in calcium, grapefruit and grapefruit juice as they might hinder the absorption of antibiotics.
• Avoid consumption of alcohol and tobacco to treat your condition effectively.
• To cure your condition effectually complete the full course of Ancef XP 281.25mg Injection even though you find symptomatic relief.

• Ancef XP 281.25mg Injection must not be mixed or administered simultaneously with calcium-containing solutions, including total parenteral nutrition.
• Regular blood tests are recommended if you take Ancef XP 281.25mg Injection for a long time to monitor changes in white blood cells, platelets and liver functioning.
• If you are about to undergo any blood or urine tests, inform your doctor that you are taking Ancef XP 281.25mg Injection as it may interfere with urine test (for sugar) and Coomb’s test results.

Bacterial infection: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect our body. Infectious or harmful bacteria can make you sick and reproduce quickly in your body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. It can target any body part and multiply very quickly. When you get infected with bacteria, you can experience generalized symptoms like fevers, chills, and fatigue. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. Few harmful bacteria that cause infections include Streptococcus, Staphylococcus, and E. coli. Anyone can become infected with a bacterial infection. But, people with weak immune systems or taking immunosuppressive medicine are more prone to bacterial infection.