Amicrez Plus 25 Tablet is used to treat depression, neuropathic pain, chronic tension-type headaches, and migraine in adults. Additionally, Amicrez Plus 25 Tablet is also used to treat bedwetting at night in children aged 6 years and above. Depression is a mood disorder that affects a person's daily life described as feelings of sadness, loss, or anger. 

Amicrez Plus 25 Tablet contains Amitriptyline, which works by affecting certain chemical messengers (serotonin, norepinephrine) in the brain, which communicate between brain cells, thereby helping in the regulation of mood and preventing depression. Besides this, Amicrez Plus 25 Tablet also the transmission of pain signals, thereby providing relief from neuropathic pain.

You are advised to take Amicrez Plus 25 Tablet as long as your doctor has prescribed it for you, depending on your medical condition and response to the treatment. In some cases, you may experience certain common side effects such as sleepiness, drowsiness, headache, irregular heartbeat, dry mouth, constipation, nausea, weight gain, slurred or slow speech, and congested nose. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue taking Amicrez Plus 25 Tablet for as long as your doctor has prescribed. Do not take Amicrez Plus 25 Tablet if you are pregnant or breastfeeding unless prescribed by the doctor. Amicrez Plus 25 Tablet causes drowsiness, sleepiness and dizziness; do not drive unless you are alert. Amicrez Plus 25 Tablet can be given to children over 6 years old if prescribed by the doctor for bedwetting. Amicrez Plus 25 Tablet should not be given to children for treating depression or neuropathic pain. Avoid consuming alcohol along with Amicrez Plus 25 Tablet as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Amicrez Plus 25 Tablet belongs to a group of medicines called tricyclic antidepressants. Amicrez Plus 25 Tablet is used to treat depression, neuropathic pain, chronic tension-type headaches, and migraine in adults. Amicrez Plus 25 Tablet is also used to treat bedwetting at night in children aged 6 years and above. Amicrez Plus 25 Tablet works by affecting certain chemical messengers (serotonin and/or norepinephrine) in the brain, which communicate between brain cells, thereby helping in regulating mood and treating depression. Amicrez Plus 25 Tablet prevents the transmission of pain signals, thereby providing relief from neuropathic pain.

• Sleepiness
• Drowsiness
• Headache
• Irregular heartbeat
• Dry mouth
• Constipation
• Nausea
• Weight gain
• Slurred or slow speech
• Congested nose

Do not take Amicrez Plus 25 Tablet if you are allergic to any of its contents if you recently had a heart attack, or heart problems, are taking other antidepressants like isocarboxazid, phenelzine, selegiline, tranylcypromine or have taken them in the last 14 days, have severe liver disease or if you have taken moclobemide (used to treat depression and social anxiety). Inform your doctor before taking Amicrez Plus 25 Tablet if you have heart rhythm problems or hypotension. Consult your doctor immediately if you have suicidal thoughts such as killing or harming yourself. Do not take Amicrez Plus 25 Tablet if you are pregnant or breastfeeding unless prescribed. Amicrez Plus 25 Tablet causes drowsiness and dizziness, do not drive unless you are alert. Amicrez Plus 25 Tablet can be given to children above 6 years if prescribed by the doctor for treating bedwetting. Amicrez Plus 25 Tablet should not be given to children for treating depression or neuropathic pain. Avoid consuming alcohol along with Amicrez Plus 25 Tablet as it could lead to increased drowsiness and dizziness. Rise slowly from sitting or lying position as Amicrez Plus 25 Tablet causes orthostatic hypotension (sudden lowering in blood pressure leading to dizziness on standing).

Drug-Drug Interactions: Amicrez Plus 25 Tablet may have interaction with pain killers (tramadol, trazodone, hydrocodone, oxycodone, acetaminophen), an antidepressant (bupropion, duloxetine, fluoxetine, sertraline), antihistamine (diphenhydramine, cetirizine), sedatives (zolpidem), muscle relaxant (cyclobenzaprine), anti-convulsant (gabapentin, lamotrigine, escitalopram, pregabalin, topiramate), anti-thyroid (levothyroxine), and anti-anxiety (alprazolam).

Drug-Food Interactions: Avoid consuming alcohol along with Amicrez Plus 25 Tablet as it may increase the sedative effects.

Drug-Disease Interactions: Amicrez Plus 25 Tablet may have interactions with disease conditions such as heart problems, anticholinergic effects, depression, seizure disorders, bone marrow suppression, diabetes, schizophrenia, bipolar disorder, acute alcohol intoxication, glaucoma, thyroid problems, pheochromocytoma, neutropenia, kidney and liver problems.

• TRAMADOL
• TRAZODONE
• HYDROCODONE
• OXYCODONE
• ACETAMINOPHEN
• BUPROPION
• DULOXETINE
• FLUOXETINE
• SERTRALINE
• DIPHENHYDRAMINE
• CETIRIZINE
• ZOLPIDEM
• CYCLOBENZAPRINE
• GABAPENTIN
• LAMOTRIGINE
• ESCITALOPRAM
• PREGABALIN
• TOPIRAMATE
• LEVOTHYROXINE SODIUM
• ALPRAZOLAM

• Maintain a healthy diet and exercise regularly helps in improving overall health and boosts self-esteem.

• Regularly attend therapy sessions.

• Perform meditation and yoga. This helps in relieving stress and provides relaxation.

• Follow a regular sleep pattern to improve the amount and quality of sleep you get.

• Include foods rich in omega fatty acids such as fish, nuts, fresh fruits, vegetables and olive oils.

• Neurotransmitters are made up of amino acids. Amino acid-rich foods such as meat, dairy products, and certain fruits and vegetables help in proper maintenance of neurotransmitters. 

• Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges and pears.

• Exercising helps in the production of the body’s natural antidepressants. It also helps in relieving stress, improving mood, boosts self-esteem, and provides restful sleep.

• Avoid smoking and alcohol consumption.

• Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Depression: It is a mood disorder characterised by the feeling of sadness, unhappiness, anger, hopelessness or loss that interferes with a person’s daily activities. Depression can also influence some chronic health conditions and relationships. The exact cause of depression is unknown, but it may be associated with mental problems, trauma, family history, drug use, and medical conditions.