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Amfosted 500 Injection 1's

Amfosted 500 Injection 1's

Prescription drug
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Composition

AMIFOSTINE-500MG

Manufacturer/Marketer

Therdose Pharma Pvt Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-25

for this medicine

About Amfosted 500 Injection

Amfosted 500 Injection belongs to the class of cytoprotective agents. It is used in reducing cumulative renal toxicity associated with repeated administration of cisplatin in patients with advanced ovarian cancer. It is also used for the reduction of the incidence of moderate to severe xerostomia in patients undergoing post-operative radiation treatment for head and neck cancer.

Amfosted 500 Injection contains Amifostine, which belongs to the class of protective agents. It works by protecting the kidneys in patients undergoing chemotherapy and radiation therapy.

Amfosted 500 Injection may cause certain side effects such as nausea, vomiting, pain at the site of injection, and injection site reactions. Inform your doctor if any of these side effects persist for longer. Amfosted 500 Injection will be administered by your physician in the hospital. Do not self-administer.

Avoid receiving Amfosted 500 Injection and inform your doctor if you are allergic to it or any other components of it. Before taking Amfosted 500 Injection, tell your doctor if you have/had liver or kidney disease, cardiac problems, skin disorders, and low calcium levels. This medicine is known to cause embryo-fetal toxicity. Hence, it is not recommended for use in pregnancy. Avoid breastfeeding while taking this Amfosted 500 Injection.

Uses of Amfosted 500 Injection

Treatment of Ovarian Cancer

Medicinal Benefits

Amfosted 500 Injection contains Amifostine, which is used in protecting kidneys from renal toxicity associated with repeated administration of cisplatin in patients with advanced ovarian cancer. It is a cytotoxic medicine that detoxifies the reactive metabolites of platinum and alkylating agents.

Directions for Use

Amfosted 500 Injection will be administered by a trained healthcare professional in the hospital setting. Hence, do not self-administer. Your doctor will decide the dose and duration of the treatment based on the severity and type of cancer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Amfosted 500 Injection

  • Nausea
  • Vomiting
  • Pain at the site of injection
  • Allergic reactions
  • Injection site reactions

Drug Warnings

To treat your condition effectually, continue receiving Amfosted 500 Injection for the period that your doctor has prescribed. Amfosted 500 Injection may cause severe cutaneous reactions, hypotension, cardiovascular problems, nausea, vomiting, and hypocalcemia. Therefore, caution should be exercised if you have/had liver or kidney disease, heart problems, and skin disorders while receiving Amfosted 500 Injection. This medicine may also cause severe hypersensitivity reactions. Hence, careful monitoring is recommended and discontinue the treatment if any severe allergic reactions occur. Inform your doctor if you are pregnant or are planning to become pregnant before starting the treatment, as this medicine is known to cause embryo-fetal toxicity. Breastfeeding should be discontinued in nursing mothers during the treatment as it passes into breast milk and may cause a possible risk to the infant. This medicine is not recommended for use in children as the safety and efficacy are not established. 

Drug Interactions

Drug-Drug Interactions: Amfosted 500 Injection may have interaction with antihypertensive drugs, calcimimetic drugs (etelcalcetide),

Drug-Food Interactions: No interactions found.

Dug-Disease Interactions: Tell your doctor if you have kidney disease, heart problems, hypotension, skin disorders, or hypocalcaemia before starting the treatment.

Drug-Drug Interactions Checker List

  • METOPROLOL
  • AMLODIPINE
  • ETELCALCETIDE
  • CILNIDIPINE
  • SPIRONOLACTONE

Habit Forming

No

Diet & Lifestyle Advise

  • Physical activity helps strengthen muscles, reduces fatigue, helps in weight loss, and gives strength. Gentle activities like 20-30 minutes of walking or swimming would be helpful.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Getting adequate sleep as resting helps improve your health and mental ability and improves attention.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath, or listening to soothing music.
  • Eat food rich in antioxidants such as berries, spinach, etc.
  • Foods containing fibre help in better digestion. These include beans, peas, lentils, whole grains, nuts, and seeds.
  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight.

Special Advise

  • Your doctor may suggest periodic blood test to monitor the function of the kidney and calcium levels due to the use of Amfosted 500 Injection.
  • Using contraceptive pills while using Amfosted 500 Injection to prevent pregnancy is advised.
  • Regular blood pressure monitoring is recommended during the treatment course to check for any changes in cardiovascular events.

Disease/Condition Glossary

Ovarian cancer: It is a common type of cancer that occurs when abnormal cells in the ovary begin to multiply out of control and form a tumor. If left untreated, the tumor can spread to other parts of the body (metastasis). This is called metastatic ovarian cancer. Symptoms may include abdominal bloating, pressure, pain, abnormal fullness after eating, difficulty eating, increased urination, and an increased urge to urinate.

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Alcohol

Consult your doctor

It is unknown whether Amfosted 500 Injection interacts with alcohol. Consult your doctor for more information.

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Pregnancy

Unsafe

Amfosted 500 Injection is not recommended for use in pregnancy as it may cause embryo-fetal toxicity and harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Amfosted 500 Injection. You should not become pregnant while you are receiving Amfosted 500 Injection. Using effective birth control methods while on treatment is suggested.

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Breast Feeding

Unsafe

Amfosted 500 Injection should not be taken if you are breastfeeding as it passes into breast milk and may harm your infant. Avoid nursing your child while on treatment with this medicine.

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Driving

Not applicable

Amfosted 500 Injection will be administered to hospitalized patients.

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Liver

Caution

If you have a pre-existing or a history of liver problems, tell your doctor before receiving this medicine. Your doctor may suggest tests to monitor your liver function while on treatment with this medicine.

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Kidney

Caution

If you have a pre-existing or a history of kidney diseases, inform your doctor before receiving Amfosted 500 Injection. Tell your doctor if you have little or no urination, swelling in your feet or ankles, or blood in your urine. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Amfosted 500 Injection is not recommended for use in children as the safety and efficacy is not established.

Country of origin

India

Manufacturer/Marketer address

Plot No's : 118 - 120, Road No. 6, Sy. No 342, ALEAP Industrial Estate, Pragathi Nagar, Kukatpally, Hyderabad - 500090, Telangana State, India
Other Info - AMF0024

FAQs

Amfosted 500 Injection is used to treat ovarian cancer.
Amfosted 500 Injection contains Amifostine, which works by protecting the kidneys in patients undergoing chemotherapy and radiation therapy.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

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