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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 10, 2024 | 7:19 PM IST
Amfirst AT 5 mg/50 mg Tablet is used to treat hypertension (high blood pressure). It contains Amlodipine and Atenolol, which relaxes and widens the constricted blood vessels. This ultimately reduces the heart's workload and makes the heart more efficient in pumping blood throughout the body. Also, it blocks stress hormones like adrenaline and epinephrine, thereby slowing down the increased heart rate. Thus, it helps lower raised blood pressure, reduces the chances of heart attack or stroke in the future. It may cause common side effects such as nausea, sleepiness, ankle swelling, headache, palpitations, low blood pressure, cold extremities, flushing (sense of warmth in the ears, face, neck, and trunk), slow heart rate, oedema (swelling), constipation, tiredness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Prescription drug

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Prescription drug
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Manufacturer/Marketer

Sinsan Pharmaceuticals Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Amfirst AT 5 mg/50 mg Tablet

Amfirst AT 5 mg/50 mg Tablet is an anti-hypertensive medication that is used to treat hypertension (high blood pressure). Hypertension (high blood pressure) is a lifelong or chronic condition in which the blood pressure against the artery walls becomes too high. This can lead to damaged blood vessels, heart disease, stroke, kidney disease, and other problems.

Amfirst AT 5 mg/50 mg Tablet contains Amlodipine (a calcium channel blocker) and Atenolol (a beta-blocker). Amlodipine acts by relaxing and widening the constricted blood vessels. This ultimately reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Atenolol works by blocking stress hormones like adrenaline and epinephrine, thereby slowing down the increased heart rate. Thus, it helps lower raised blood pressure, reducing the chances of heart attack or stroke in the future.

Take Amfirst AT 5 mg/50 mg Tablet as prescribed by your doctor. Depending upon your medical condition, you are advised to take Amfirst AT 5 mg/50 mg Tablet for as long as your doctor has prescribed it for you. The most common side effects of Amfirst AT 5 mg/50 mg Tablet are nausea, sleepiness, ankle swelling, headache, palpitations, low blood pressure, cold extremities, flushing (sense of warmth in the ears, face, neck, and trunk), slow heart rate, oedema (swelling), constipation, tiredness. They do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Inform your doctor if you have had an allergic reaction to Amfirst AT 5 mg/50 mg Tablet , are pregnant or are planning to get pregnant, are breastfeeding, have liver disease, kidney disease, heart failure, a heart valve problem or a history of a heart attack. It is recommended to monitor your blood pressure if you have ever had a stroke or heart attack or are currently taking other blood pressure-lowering pills. It is advised to continue taking this drug and not stop taking it suddenly without consulting your doctor. It is advisable to drink plenty of fluids while taking this medicine. However, kidney patients should avoid taking plenty of fluids.

Uses of Amfirst AT 5 mg/50 mg Tablet

Treatment of Hypertension (high blood pressure).

Medicinal Benefits

Amfirst AT 5 mg/50 mg Tablet is a combination drug containing 'anti-hypertensive' drugs containing Amlodipine (a calcium channel blocker) and Atenolol (a beta-blocker) primarily taken for the treatment of hypertension (high blood pressure). Amfirst AT 5 mg/50 mg Tablet reduces the heart's workload making the heart more efficient at pumping blood throughout the body and relaxing and widening the blood vessel. Thus, it collectively helps lower high blood pressure, reducing the chances of heart attack or stroke.

Directions for Use

Swallow the mediscine as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Amfirst AT 5 mg/50 mg Tablet

  • Nausea

  • Sleepiness

  • Ankle swelling

  • Headache 

  • Palpitations

  • Cold extremities

  • Flushing (sense of warmth in the face, ears, neck, and trunk)

  • Slow heart rate

  • Oedema (swelling) 

  • Constipation

  • Tiredness

Drug Warnings

 Inform your doctor if you have had an allergic reaction to Amfirst AT 5 mg/50 mg Tablet , are pregnant or are planning to get pregnant, are breastfeeding, have liver disease, kidney disease, heart failure, a heart valve problem, or have a history of a heart attack. And also disclose to your doctor all the prescription and over-the-counter medications you use, including vitamins, minerals, herbal products, and drugs other prescribed medications. You must closely monitor your blood pressure if you have ever had a stroke or heart attack or are currently taking other blood pressure-lowering pills. Do not start using a new medication without telling your doctor. And also, keep your doctor informed if you are taking anti-diabetic medicines along with Amfirst AT 5 mg/50 mg Tablet . Amfirst AT 5 mg/50 mg Tablet contains Atenolol, a category D pregnancy drug, so it should not be taken if you are pregnant, planning to become pregnant, or breastfeeding, as it can harm the baby. Lifestyle changes are beneficial in achieving optimum outcomes with Amfirst AT 5 mg/50 mg Tablet and keeping blood pressure under check. A low salt diet, daily physical activity, losing weight in the case of people who are obese, etc., are the mainstay of the treatment of hypertension.

Drug Interactions

 Drug-Drug Interactions: Amfirst AT 5 mg/50 mg Tablet is known to interact with potassium-sparing diuretics (amiloride, eplerenone, spironolactone), anti-depression medication (lithium), high blood pressure-lowering pills (benazepril, metoprolol, ramipril, hydrochlorothiazide), drugs used to control lipid levels in the blood (atorvastatin, simvastatin), medicines to treat erectile dysfunction (sildenafil), antibiotics (clarithromycin, erythromycin, rifampin), antifungal (itraconazole, ketoconazole), anti-HIV drugs (ritonavir), anti-epilepsy medicines (carbamazepine, phenytoin, phenobarbital, primidone), immune-suppressing drugs (cyclosporine, tacrolimus) and painkillers (ibuprofen, aspirin).

Drug-Food Interactions: Amfirst AT 5 mg/50 mg Tablet is known to interact with grapefruit juice and alcohol. So, it should not be taken along with the Amfirst AT 5 mg/50 mg Tablet .

Drug-Disease Interactions: Amfirst AT 5 mg/50 mg Tablet is known to interact if you have kidney or liver problems, heart disease, diabetes, myasthenia gravis (muscle weakness), glaucoma (increased eye pressure), asthma, hypotension (low blood pressure), cardiogenic shock (when the heart fails to pump required blood to the body).

Drug-Drug Interactions Checker List

  • AMILORIDE
  • EPHEDRINE
  • SPIRONOLACTONE
  • LITHIUM
  • BENAZEPRIL
  • METOPROLOL
  • RAMIPRIL
  • HYDROCHLOROTHIAZIDE
  • ATORVASTATIN
  • SIMVASTATIN
  • SILDENAFIL
  • CLARITHROMYCIN
  • ERYTHROMYCIN
  • RIFAMPICIN
  • ITRACONAZOLE
  • KETOCONAZOLE
  • RITONAVIR
  • CARBAMAZEPINE
  • PHENYTOIN
  • PHENOBARBITAL
  • PRIMIDONE
  • CYCLOSPORINE
  • TACROLIMUS
  • IBUPROFEN
  • ASPIRIN

Habit Forming

No

Diet & Lifestyle Advise

  • Create a well-balanced and healthy diet that includes vegetables, fruits, whole grains, legumes, omega-3-rich foods, and lean protein sources.

  • Keep your weight under control with a BMI of 19.5-24.9.

  • Avoid chronic stress, as it can raise your blood pressure.

  • Spend time with your loved ones to cope with stress and practice mindfulness techniques.

  • Be mindful of salt; consume no more than 2,300 mg each day.

  • Limit or avoid alcohol consumption.

  • Quitting smoking is the best strategy to lower the risk of heart disease.

Disease/Condition Glossary

Hypertension: The blood exerts increased pressure on the walls of blood vessels leading to hypertension. High blood pressure is expressed as systolic/diastolic pressure. Systolic pressure is the pressure in the arteries when the heart beats or pumps out blood. Diastolic pressure is the pressure in the arteries between the heartbeats. Blood pressure is measured in millimetres of mercury (mmHg) by a blood pressure monitor called a sphygmomanometer. Some of the symptoms are headache, dizziness, nosebleeds, altered vision, chest pain, weakness, and shortness of breath. However, most of the time, the signs and symptoms of hypertension are none.

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Alcohol

Caution

You are recommended not to consume alcohol and Amfirst AT 5 mg/50 mg Tablet to avoid unpleasant side effects like lowering blood pressure (hypotension).

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Pregnancy

Caution

Amfirst AT 5 mg/50 mg Tablet contains atenolol, which is a pregnancy category D drug. It is known to harm the baby if taken during pregnancy. So it is better to avoid intake of Amfirst AT 5 mg/50 mg Tablet in pregnant women in their second and third trimesters.

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Breast Feeding

Caution

Amfirst AT 5 mg/50 mg Tablet can pass through the breast milk and harm the baby, so it should not be taken while breastfeeding.

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Driving

Caution

Drive with caution. Amfirst AT 5 mg/50 mg Tablet usually causes drowsiness and affects driving ability.

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Liver

Caution

Amfirst AT 5 mg/50 mg Tablet to be taken with caution, especially if you have had a history of liver disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

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Kidney

Caution

Amfirst AT 5 mg/50 mg Tablet to be taken with caution, especially if you have had a history of liver disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

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Children

Caution

Amfirst AT 5 mg/50 mg Tablet is not recommended for children below six years of age without a doctor's consent. The dose is to be adjusted and guided by a child specialist only for children above six years.

Country of origin

India

Manufacturer/Marketer address

102-103, Park Plaza, Opp. Kamla Nehru Park, Off. Bhandarkar Road, Deccan Gymkhana, Pune, Maharashtra 411004
Other Info - AMF0040

Author Details

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FAQs

Amfirst AT 5 mg/50 mg Tablet belongs to the class of anti-hypertensive medication used to treat hypertension (high blood pressure).
Amfirst AT 5 mg/50 mg Tablet is a combination of anti-hypertensive medications. Amlodipine acts by relaxing and widening the constricted blood vessels. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Atenolol works by slowing down the heart rate of the heart. Thus, it collectively helps lower high blood pressure, reducing the chances of heart attack or stroke.
No, you are advised to inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Depending upon your current blood pressure readings, there is a possibility your doctor may lower your medicine dosage and not recommend discontinuing it. If you suddenly stop taking Amfirst AT 5 mg/50 mg Tablet , it may cause a jump in blood pressure, chest pain, or can even lead to a heart attack.
Yes, Amfirst AT 5 mg/50 mg Tablet is known to cause ankle swelling upon long-term use. Please try to keep your feet up when sitting for long hours. If the problem persists still, consult your doctor and do as advised.
High blood pressure during pregnancy is called 'Pregnancy-induced hypertension (PIH). It is harmful to both the baby and the mother. In the mother, very high blood pressure can cause seizures (fits), headache, swelling of feet, kidney damage, and a higher risk of bleeding during pregnancy and during delivery. This can also affect the baby by causing abnormal fetal heart rate, risk of stillbirth and a small baby. So, during pregnancy, you should have regular blood pressure monitoring. Visit your Obstetrician if you have any concerns about blood pressure during pregnancy.
It is also known as fluid retention or fluid overload. Due to oedema, the affected area starts swelling up. If it does not subside, please consult your doctor immediately.
Yes, Amfirst AT 5 mg/50 mg Tablet can cause dizziness sometimes, so it is advised to avoid driving or operating heavy machinery while taking Amfirst AT 5 mg/50 mg Tablet . In case you feel dizzy or lightheaded, it is recommended to rest for some time until you feel better.
Yes, Amfirst AT 5 mg/50 mg Tablet is contraindicated in people with known allergies to any of this medicine's components. It should be avoided in people with severe kidney or liver impairment and people with anuria (reduction or absence of urine). It should also be avoided for use in pregnant women who are in the second and third trimesters of their pregnancy.
The effect of this medicine can be observed within 2 to 4 hours.
Usually, treatment with Amfirst AT 5 mg/50 mg Tablet is long-term, even for the rest of your life. Talk to your doctor if you want to stop taking Amfirst AT 5 mg/50 mg Tablet .
You should take your medications regularly at the same time. In addition, changing your lifestyle may also help to control blood pressure. These changes include eating a healthy diet low in fat and salt, exercising at least half an hour every day, maintaining a healthy weight, reducing alcohol consumption, and quitting smoking habits.
The most common side effects of Amfirst AT 5 mg/50 mg Tablet are nausea, sleepiness, ankle swelling, headache, palpitations, low blood pressure, cold extremities, flushing (sense of warmth in the ears, face, neck, and trunk), slow heart rate, oedema (swelling), constipation, tiredness. They do not require medical attention and gradually resolve over time. However, if the side effects persist, contact your doctor.
Amfirst AT 5 mg/50 mg Tablet contains Amlodipine (a calcium channel blocker) and Atenolol (a beta-blocker).
You should take your medications regularly at the same time. In addition, changing your lifestyle may also help to control blood pressure. These changes include eating a healthy diet low in fat and salt, exercising at least half an hour every day, maintaining a healthy weight, reducing alcohol consumption, and quitting smoking habits.
Dizziness may also occur, especially when you get up suddenly from a lying or sitting position. If you feel dizzy, lie down so you do not faint. Then, sit for a few moments before standing to prevent the dizziness from returning. If you faint, call your doctor right away.
Amfirst AT 5 mg/50 mg Tablet is generally safe to take for a long time. In fact, it works best when you take it for a long time. Consult your doctor if you experience any side effects that persist.
You can eat and drink normally while taking Amfirst AT 5 mg/50 mg Tablet . Eating a healthy, balanced diet can help if you have high blood pressure or another heart condition.

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