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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Jan 1, 2025 | 2:49 PM IST
Amantrel ER 129 Tablet is used to treat Parkinson's disease symptoms. It plays a vital role in treating symptoms such as difficulty moving, muscle stiffness, and tremors. It contains Amantadine, which increases dopamine (a chemical) level in the brain, responsible for improving body movement coordination. Thus, it effectively helps in performing daily functions in a better way and improving quality of life. In some cases, it may cause side effects like dry mouth, constipation, balance disorder (loss of balance), blurred vision, insomnia (difficulty sleeping), and peripheral oedema. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Synonym :

AMANTADINE HYDROCHLORIDE

Composition :

AMANTADINE-129MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Apr-26

About Amantrel ER 129 Tablet

Amantrel ER 129 Tablet contains a class of medication called dopamine agonists used to treat Parkinson's disease symptoms. It plays a vital role in treating symptoms such as difficulty moving, muscle stiffness, and tremors. Parkinson's disease is a nervous system disorder that causes movement, muscle control, balance, and other similar conditions.  In addition to this, it also prevents symptoms of influenza (a viral infection).

Amantrel ER 129 Tablet contains amantadine (dopamine agonist), which is an anti-Parkinson's drug. It helps treat Parkinson's disease by increasing dopamine (a chemical) level in the brain, responsible for improving body movement coordination. Thus, it effectively helps in performing daily functions in a better way and improving quality of life.

In some cases, Amantrel ER 129 Tablet may cause side effects like dry mouth, constipation, balance disorder (loss of balance), blurred vision, insomnia (difficulty sleeping), and peripheral oedema. Most of these side effects of Amantrel ER 129 Tablet are temporary, do not require medical attention, and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not take Amantrel ER 129 Tablet if you are allergic to any of its components, have severe liver or kidney problems, or have epilepsy. Check with your doctor if you're pregnant, currently breastfeeding, or taking any other prescribed or non-prescribed medicines. Also, do not stop Amantrel ER 129 Tablet abruptly, as it may lead to severe side effects. Consult your doctor, and he/she might lower the dose gradually.

Uses of Amantrel ER 129 Tablet

Treatment of Parkinson's disease.

Medicinal Benefits

Amantrel ER 129 Tablet contains amantadine (dopamine agonist), which is an anti-Parkinson's drug. It helps treat Parkinson's disease by increasing dopamine (a chemical) level in the brain, responsible for improving body movement coordination. Thus, it effectively helps in performing daily functions in a better way and improving quality of life.

Side Effects of Amantrel ER 129 Tablet

  • Dry mouth
  • Constipation
  • Balance disorder (loss of balance)
  • Blurred vision
  • Insomnia (difficulty sleeping)
  • Peripheral edema

Directions for Use

Take Amantrel ER 129 Tablet with or without food as advised by a doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Amantrel ER 129 Tablet if you are allergic to amantadine or any of its ingredients. Inform your doctor about all other OTC medications, vitamins, nutritional supplements, and herbal products you are taking or are planning to take. If you have kidney or liver disease, mental illness, glaucoma (increased pressure in the eye can lead to a gradual loss of vision), epilepsy, a sleep disorder, eczema (dry, itchy skin with red, scaly rashes), urinary tract infections, heart failure, hypotension (low blood pressure), or if you drink or have ever consumed large amounts of alcohol, Amantrel ER 129 Tablet should be taken with caution and only if a doctor prescribes you. Tell your doctor if you are pregnant or are breastfeeding before starting Amantrel ER 129 Tablet as a dose adjustment may be required if the benefits outweigh the risks. Amantrel ER 129 Tablet may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position, especially when you start taking Amantrel ER 129 Tablet so please get up gradually. Also, do not take any live vaccination for at least 48 hours after the last dose of Amantrel ER 129 Tablet . Avoid dairy products as it may cause disease progression, and take some calcium supplements to avoid their deficiency.

Therapeutic Class

ANTIPARKINSON AGENTS

Drug-Drug Interactions

verifiedApollotooltip
AmantadineIopamidol
Severe
AmantadineAclidinium bromide
Severe

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Try to include heart-healthy omega 3 fatty acid containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil.

  • Include turmeric or yellow mustard in your diet to avoid constipation caused by Parkinson’s disease and increase the intake of fluids to stay hydrated.

  • Caffeine can help in slowing down the progression of the disease.

  • Take enough of Vitamin D and fresh air as it is known to improve the symptoms of Amantrel ER 129 Tablet .

Habit Forming

No

How Amantrel ER 129 Tablet Works

Amantrel ER 129 Tablet contains amantadine (dopamine agonist), which is an anti-Parkinson's drug. It helps treat Parkinson's disease by increasing dopamine (a chemical) level in the brain, responsible for improving body movement coordination. Thus, it effectively helps in performing daily functions in a better way and improving quality of life.

What if I have taken an overdose of Amantrel ER 129 Tablet

Do not take more than the prescribed dose of Amantrel ER 129 Tablet as it may cause overdose. The symptoms of overdose include difficulty breathing, decreased urination, irregular or fast heartbeat, confusion, problems with coordination, stiff or rigid arms/legs, hallucinations and fear/irritability/aggressive behaviour. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.
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Alcohol

Unsafe

Intake of alcohol with Amantrel ER 129 Tablet may damage your liver. Therefore, you are recommended to avoid consumption of alcohol with Amantrel ER 129 Tablet .

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Pregnancy

Caution

Amantrel ER 129 Tablet is a pregnancy Category C medicine. It is not known whether Amantrel ER 129 Tablet will affect pregnant women or fetus. Therefore, Amantrel ER 129 Tablet is given to pregnant women only if doctor thinks benefits are greater than risks.

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Breast Feeding

Caution

Amantrel ER 129 Tablet is excreted in human milk. But the amount of Amantrel ER 129 Tablet absorbed by the nursing infant is unknown. So, it should not be taken while breastfeeding.

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Driving

Unsafe

Amantrel ER 129 Tablet can affect alertness and coordination. So, operating machinery which requires concentration should be avoided.

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Liver

Unsafe

Amantrel ER 129 Tablet is unsafe, especially if you have a history of liver diseases/conditions. Your doctor may have to adjust the dose if there are symptoms of nausea, vomiting, loss of appetite, dark-colored urine, or yellowing of skin/eye.

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Kidney

Caution

Amantrel ER 129 Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Safe if prescribed

Amantrel ER 129 Tablet can be given to children but under medical supervision. Amantrel ER 129 Tablet is prescribed to the children to treat complicated urinary tract infections, anthrax infection, or plague infection.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - AMA0130

Author Details

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FAQs

Amantrel ER 129 Tablet is used to treat Parkinson's disease symptoms. It plays a vital role in treating symptoms such as difficulty moving, muscle stiffness, and tremors.
Amantrel ER 129 Tablet works by increasing dopamine (a chemical) level in the brain, responsible for improving body movement coordination. Thus, it effectively helps in performing daily functions in a better way and improving quality of life.
No, Amantrel ER 129 Tablet should be taken in the dose and duration as advised by the doctor. If you take it in more than the recommended dose, it might cause unpleasant side effects. If you think your symptoms are not improving, please consult your doctor.
If you miss a dose of Amantrel ER 129 Tablet , take the missed dose as soon as you remember it. However, if it's almost time for the next dose, do not take a double dose to make up for a missed one.
No, Amantrel ER 129 Tablet should not be taken if you have epilepsy as it might increase your chances of seizures. Please consults your doctor before starting Amantrel ER 129 Tablet .
You should inform your doctor, and he might stop the use of Amantrel ER 129 Tablet before the surgery.
Do not stop taking Amantrel ER 129 Tablet without talking to your doctor. If you suddenly stop taking Amantrel ER 129 Tablet , you may experience confusion, fever, mental state changes, or severe muscle stiffness. Your doctor will probably decrease your dose gradually depending upon your disease condition.
Amantadine is a dopamine agonist used to treat Parkinson's disease and its symptoms, including dyskinesia (sudden uncontrolled movements).
Amantadine may cause constipation as a common side effect. Usually, it is temporary, does not require medical attention, and gradually resolves over time. However, if this persistent, reach out to your doctor.
Yes, in some cases, Amantrel ER 129 Tablet has been used for neuropathic pain.
Amantrel ER 129 Tablet contains Amantadine as an active ingredient.
Amantrel ER 129 Tablet may cause some people to become dizzy, drowsy, or lightheaded, leading to tiredness or fatigue.
If you suddenly stop taking Amantrel ER 129 Tablet , you may experience confusion, fever, mental state changes, or severe muscle stiffness. Depending on your disease condition, your doctor will decrease your dose gradually, if necessary.
Amantrel ER 129 Tablet is not a dopamine agonist. It may inhibit the reuptake of dopamine and increase the synthesis and release of dopamine.
Individual needs may vary from person to person, so it should be used as directed by the physician.
Yes, Amantrel ER 129 Tablet can be taken with or without food.
In rare cases, Amantrel ER 129 Tablet may cause anxiety and feeling overexcited. If you experience any of these symptoms or if they persist, please consult the doctor.
Overdose symptoms may include confusion, agitation, behaviour changes, hallucinations, severe headache or pounding in your ears, muscle stiffness, problems with balance or walking, trouble breathing, Tachycardia (fast heartbeats) and seizures.
Limited research is available. Consult your doctor if you have any questions or concerns regarding this.
With continued Amantrel ER 129 Tablet use, decreased weight and body mass index may occur. Seek medical attention if you observe any significant or sudden changes.
Amantrel ER 129 Tablet may cause side effects like dry mouth, constipation, balance disorder (loss of balance), blurred vision, insomnia (difficulty sleeping), and peripheral oedema. Most of these side effects of Amantrel ER 129 Tablet are temporary, do not require medical attention, and gradually resolve over time. However, if the side effects persist, contact your doctor.

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