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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Dec 7, 2024 | 2:26 PM IST
Alex Plus Syrup is used to treat dry cough. Additionally, it also treats allergy symptoms such as sneezing, runny nose, throat irritation or watery eyes. It increases the volume of fluid in the airways, reduces the stickiness of mucus, and removes it from the airways. It works by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Thus, it decreases the need to cough. Also, it works by contracting and narrowing the blood vessels. Thereby, provides relief from congestion and decreases mucus production. Additionally, it works by blocking the action of histamine, a substance responsible for causing allergic reactions. Some people may experience side effects such as nausea, stomach upset, vomiting, loss of appetite, drowsiness, headache, diarrhoea, dizziness or skin rash. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Prescription drug

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Manufacturer/Marketer

Glenmark Pharmaceuticals Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Alex Plus Syrup

Alex Plus Syrup belongs to a class of medications called ‘expectorants’ primarily used to treat dry cough. Additionally, Alex Plus Syrup also treats allergy symptoms such as sneezing, runny nose, throat irritation or watery eyes. Coughing (dry or productive) is a body’s way of clearing irritants (like allergens, mucus or smoke) from airways and preventing infection. There are two types of coughs, namely: Dry cough and chesty cough. A dry cough is tickly and doesn't produce any vicious or thick mucus, while a chesty cough (wet cough) means mucous or sputum is produced to help clear your airways. 

Alex Plus Syrup is a combination of four drugs, namely: Guaifenesin (expectorant), Dextromethorphan (cough suppressant), Phenylephrine (decongestant) and Chlorpheniramine (antihistamine). Guaifenesin belongs to the class of expectorants that increase the volume of fluid in the airways, reduce the stickiness of mucus, and remove it from the airways. Dextromethorphan is a cough suppressant that works by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Thus, it decreases the need to cough. Phenylephrine is a decongestant that works by contracting and narrowing the blood vessels. Thereby, provides relief from congestion and decreases mucus production. Chlorpheniramine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions.

Take Alex Plus Syrup as prescribed. Your doctor will recommend how often you take Alex Plus Syrup based on your medical condition. Some people may experience nausea, stomach upset, vomiting, loss of appetite, drowsiness, headache, diarrhoea, dizziness or skin rash. Most of these side effects of Alex Plus Syrup do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Alex Plus Syrup or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Alex Plus Syrup. Alex Plus Syrup is not recommended for children below 12 years of age. If you are about to undergo any medical tests or surgery, please inform your doctor that you are taking Alex Plus Syrup. Drink plenty of fluids while taking Alex Plus Syrup to loosen the congestion. If you have high blood pressure, fits, glaucoma, hyperthyroidism (overactive thyroid), chronic bronchitis, asthma, cough with mucus, cough caused by smoking, chronic bronchitis or emphysema (a lung condition causing shortness of breath), chronic obstructive pulmonary disease (COPD), blockage in stomach or intestines, phenylketonuria (a congenital disability that causes accumulation of amino acid, phenylalanine in the body), enlarged prostate, pheochromocytoma (tumour in the adrenal glands), kidney, liver, heart or urinary problems, inform your doctor before taking Alex Plus Syrup.

Uses of Alex Plus Syrup

Treatment of Dry cough

Medicinal Benefits

Alex Plus Syrup is a combination of four drugs, namely: Guaifenesin, Dextromethorphan, Phenylephrine, and Chlorpheniramine. Guaifenesin belongs to the class of expectorants that works by increasing the volume of fluid in the airways, reducing the stickiness of mucus, and helping to remove it from the airways. Dextromethorphan is a cough suppressant that blocks the transmission of nerve signals from the cough center in the brain to the muscles that produce cough. Thus, it decreases the need to cough. Phenylephrine is a decongestant that works by contracting and narrowing the blood vessels. Thereby, providing relief from congestion and decreasing mucus production. Chlorpheniramine is an antihistamine (anti-allergic drug) that works by blocking the action of histamine, a substance responsible for causing allergic reactions, and provides relief from symptoms of allergy such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness.

Directions for Use

Shake the bottle well before use. Check the label for directions and take Alex Plus Syrup with or without food in doses as prescribed by your doctor with the help of a measuring cup that is provided with the pack.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Alex Plus Syrup

  • Nausea
  • Stomach upset
  • Vomiting
  • Loss of appetite
  • Drowsiness
  • Headache
  • Diarrhoea
  • Dizziness
  • Skin rash

Drug Warnings

If you are allergic to Alex Plus Syrup or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Alex Plus Syrup. Alex Plus Syrup is not recommended for children below 12 years of age. If you are about to undergo any medical tests or surgery, please inform your doctor that you are taking Alex Plus Syrup. Avoid using Alex Plus Syrup if you have taken medicines such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine, and methylene blue injection in the past 14 days. If you have high blood pressure, fits, glaucoma, hyperthyroidism (overactive thyroid), chronic bronchitis, asthma, cough with mucus, cough caused by smoking, chronic bronchitis or emphysema (a lung condition causing shortness of breath), chronic obstructive pulmonary disease (COPD), blockage in stomach or intestines, phenylketonuria (a birth defect that causes accumulation of amino acid, phenylalanine in the body), enlarged prostate, pheochromocytoma (tumor in the adrenal glands), kidney, liver, heart or urinary problems, inform your doctor before taking Alex Plus Syrup.

Drug Interactions

Drug-Drug Interaction: Alex Plus Syrup may have interaction with anti-allergic drugs (diphenhydramine, cetirizine), antidepressants (duloxetine, sertraline, escitalopram), narcotic analgesics (hydrocodone, codeine), antianxiety drug (alprazolam), central nervous system stimulants (methylphenidate), antipsychotics  (quetiapine), medicines used to treat irregular heartbeats  (quinidine), anticonvulsants (pregabalin), a central nervous system stimulant (amphetamine).

Drug-Food Interaction: Avoid or limit the intake of chocolate and caffeine-containing foods such as cocoa beans and tea leaves with Alex Plus Syrup as they may increase the risk of severity of side effects. Also, avoid consumption of alcohol with Alex Plus Syrup as it may increase the risk of adverse effects such as drowsiness, dizziness, or difficulty in concentrating.

Drug-Disease Interaction: If you have high blood pressure, fits, glaucoma, hyperthyroidism (overactive thyroid), chronic bronchitis, asthma, cough with mucus, cough caused by smoking, chronic bronchitis or emphysema (a lung condition causing shortness of breath), chronic obstructive pulmonary disease (COPD), blockage in stomach or intestines, phenylketonuria (a birth defect that causes accumulation of amino acid, phenylalanine in the body), enlarged prostate, pheochromocytoma (tumor in the adrenal glands), kidney, liver, heart or urinary problems, inform your doctor before taking Alex Plus Syrup.

Drug-Drug Interactions Checker List

  • DIPHENHYDRAMINE
  • CETIRIZINE
  • DULOXETINE
  • SERTRALINE
  • ESCITALOPRAM
  • HYDROCODONE
  • CODEINE
  • ALPRAZOLAM
  • METHYLPHENIDATE
  • QUETIAPINE
  • QUINIDINE
  • PREGABALIN
  • AMPHETAMINE

Habit Forming

No

Diet & Lifestyle Advise

  • Avoid dairy products such as milk as they may increase mucus production. Also, avoid processed or refined foods to have relief from cough. Instead replace baked foods, fried foods, white bread, white pasta, French fries, sugary desserts and chips with green leafy vegetables.
  • Drink plenty of fluids to avoid dry throat while you have a cough and loosen mucus.
  • Avoid citrus fruits as they may worsen the cough. Eat fruits rich in water content such as pears, watermelon, peaches and pineapples.

Special Advise

  • You are recommended to inform your doctor that you are taking Alex Plus Syrup before undergoing any medical tests or surgery.
  • Drink plenty of fluids while taking Alex Plus Syrup to loosen the congestion of nasal passage and airways. If you are a kidney patient, ask a doctor before taking fluid. 

Disease/Condition Glossary

Cough: Coughing is a body’s way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection. Coughs may be dry or productive. A productive cough (wet cough) brings up sputum (phlegm, mucus, and other matter) from the lungs. Cough is commonly caused as a response to allergy or viral infection but coughing up mucus is possibly an indication of infection in the respiratory tract. If you are coughing thick, solid white mucus, it indicates you may have a bacterial infection in the airways. If the mucus is clear or light-colored, it indicates you may have allergies or a minor infection in the respiratory tract, and yellow or green mucus indicates a respiratory infection.

Allergies: These occur when foreign elements known as allergens attack and invade our body, thereby causing the release of histamines. This chemical messenger 'histamines' causes swelling, inflammation, redness, itchiness, itchy/watery nose and throat, and watery eyes. Allergies generally occur due to chemicals, air pollution, pet danders, dust, pollen hairs, seasonal allergies like hay fever, etc.

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Alcohol

Unsafe

Avoid consumption of alcohol with Alex Plus Syrup as it may increase adverse effects. Please consult a doctor before consuming alcohol with Alex Plus Syrup.

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Pregnancy

Caution

Please consult a doctor if you are pregnant. Alex Plus Syrup is given to pregnant women only if the doctor thinks benefits outweigh risks.

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Breast Feeding

Caution

It is unknown whether Alex Plus Syrup is excreted in human milk. Alex Plus Syrup is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks.

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Driving

Caution

Alex Plus Syrup may impair thinking or cause blurred vision in some people. Therefore, drive only if you are alert after taking Alex Plus Syrup.

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Liver

Caution

Take Alex Plus Syrup with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Alex Plus Syrup with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Consult your doctor

Please consult a doctor if you have any concerns regarding the usage of Alex Plus Syrup for children.

Country of origin

India

Manufacturer/Marketer address

Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai ? 400 026.
Other Info - ALE0041

Author Details

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FAQs

Alex Plus Syrup is used to treat dry cough. Additionally, it also treats allergy symptoms such as sneezing, runny nose, throat irritation or watery eyes.
Alex Plus Syrup contains Guaifenesin, Dextromethorphan, Phenylephrine and Chlorpheniramine. Guaifenesin belongs to the class of expectorants that works by increasing the volume of fluid in the airways, reduce the stickiness of mucus and helps to remove it from airways. Dextromethorphan is a cough suppressant that blocks the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Thus, decreases the need to cough. Phenylephrine is a decongestant that works by contracting and narrowing the blood vessels. Thereby, provides relief from congestion and decreases mucus production. Chlorpheniramine is an antihistamine (anti-allergic drug) that works by blocking the action of histamine, a substance responsible for causing allergic reactions and provides relief from symptoms of allergy.
Alex Plus Syrup may be used to provide relief from allergic symptoms such as sneezing, runny nose, throat irritation or watery eyes. Alex Plus Syrup contains Triprolidine, an anti-allergic drug that works by blocking the action of histamine, a substance responsible for causing allergic reactions.
You are not recommended to take Alex Plus Syrup with selegiline or other MAO inhibitors such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine and methylene blue injection at the same time as it may cause severe high blood pressure which may lead to stroke. Therefore, if you have taken any of these medicines in the past 14 days, avoid taking Alex Plus Syrup and consult a doctor for proper advice.
You are recommended to avoid taking Alex Plus Syrup if you have asthma, enlarged prostate, blockage in stomach or intestines, glaucoma or if you are unable to urinate. However, please consult a doctor if you have any of these conditions before taking Alex Plus Syrup.
You are not recommended to take Alex Plus Syrup with duloxetine as it may lead to a severe condition called ‘serotonin syndrome’ and cause symptoms such as blurred vision, stomach cramps, diarrhoea, hallucination, extreme changes in blood pressure, confusion, excessive sweating, increased heart rate, fever, shivering or shaking, tremor, incoordination, muscle spasm or stiffness. However, please consult a doctor before taking Alex Plus Syrup with other medicines.
You are recommended to take Alex Plus Syrup for as long as your doctor has prescribed it. However, if the symptoms persist or worsen with rash, fever or persistent headache after 1 week of using Alex Plus Syrup, please consult your doctor.
Alex Plus Syrup is a combination medication containing four active ingredients: Guaifenesin (expectorant), Dextromethorphan (cough suppressant), Phenylephrine (decongestant), and Chlorpheniramine (antihistamine), used to relieve allergy symptoms and dry cough.
Under directed instructions, Alex Plus Syrup is considered safe to use. However, it may have adverse effects and possible drug interactions, just like any other medication. To prevent negative consequences, you must listen to your doctor's advice and let them know about any current or pre-existing medical issues or drug history.
Alex Plus Syrup may cause nausea and vomiting, a common side effect in some individuals. In most cases, nausea and vomiting subsides as your body adjusts to the medication. However, if these side effects worsen or persist, please consult your doctor for guidance.
Alex Plus Syrup may cause sleepiness or dizziness, a common side effect in some individuals. To ensure your safety, rest for a while after taking the medication and avoid driving or operating heavy machinery. Sleepiness or dizziness usually subsides as your body adjusts to the medication. However, if the drowsiness worsens or persists, please consult your doctor for guidance.
No, you should not take more of this medication than prescribed. Taking more than the suggested amount raises the chance of side effects and may be potentially harmful. If you have any concerns, speak to your doctor.
Yes, there are some contraindications associated with the use of Alex Plus Syrup. People who are allergic to its ingredients should avoid using it. Pregnant and breastfeeding women should consult their doctor before use. It is also not recommended for children under 12 years old. Additionally, individuals with certain medical conditions, such as high blood pressure, glaucoma, hyperthyroidism, chronic bronchitis, asthma, and kidney, liver, heart, or urinary problems, should inform their doctor before taking this medication.
The recommended storage condition for Alex Plus Syrup is to store it in its original container in a cool, dry place, out of direct sunlight, and out of the reach of children.
The common side effects of Alex Plus Syrup may include nausea, stomach upset, vomiting, loss of appetite, drowsiness, headache, diarrhoea, dizziness, or skin rash. Most of these side effects of Alex Plus Syrup do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

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