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Adriamycin 50 mg Injection is an anti-cancer medicine used to treat cancer. It contains Doxorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs; this causes double-helix DNA to be uncoiled, destroying DNA and RNA synthesis. Thus, it treats cancer.
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About Adriamycin 50 mg Injection
Adriamycin 50 mg Injection is an anti-cancer medicine used in the treatment of cancer. Cancer is a disease where the cells grow abnormally and divide uncontrollably. Adriamycin 50 mg Injection is primarily used as adjuvant chemotherapy in women with axillary lymph nodes with involvement resection of breast cancer (abnormal growth in the cells of the breast). It is also used to treat neuroblastoma (cancer that starts in nerve cells and primarily affects children) and Wilms' tumor (a form of kidney cancer that affects children).
Adriamycin 50 mg Injection contains Doxorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, destroying DNA and RNA synthesis.
Adriamycin 50 mg Injection may cause certain side effects such as nausea, headache, abdominal pain, loss of appetite, vomiting, dizziness, mouth sores, tiredness, back pain, red discoloration of urine, diarrhea, and pain at the site of injection. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. A trained healthcare doctor will administer Adriamycin 50 mg Injection. So, do not self-administer. Your doctor will decide the dose of the medicine based on your health condition.
Adriamycin 50 mg Injection should be avoided if you are allergic to it or any other components of this medicine. It is contraindicated in patients having severe myocardial insufficiency, a recent history of myocardial infarction (MI), severe persistent drug-induced myelosuppression, and severe liver disease. Hence, if you have any such conditions, inform your doctor. Inform your doctor if you have any cardiovascular conditions, liver/kidney disease, or taking any CYP3A4 or CYP2D6 inducers medication, as it can cause adverse effects. Adriamycin 50 mg Injection is known to cause embryo-fetal toxicity. Hence, if you are pregnant or breastfeeding, inform your doctor beforehand.
Uses of Adriamycin 50 mg Injection
Medicinal Benefits
Adriamycin 50 mg Injection contains Doxorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis. Adriamycin 50 mg Injection is also used in the treatment of acute lymphoblastic leukaemia, acute myeloblastic leukaemia, Hodgkin lymphoma, Non-Hodgkin lymphoma, metastatic breast cancer, metastatic Wilms’ tumour, metastatic neuroblastoma, metastatic soft tissue sarcoma, metastatic bone sarcomas, metastatic ovarian carcinoma, metastatic transitional cell bladder carcinoma, metastatic thyroid carcinoma, metastatic gastric carcinoma, metastatic bronchogenic carcinoma.
Side Effects of Adriamycin 50 mg Injection
Directions for Use
Storage
Drug Warnings
Adriamycin 50 mg Injection should be avoided if you are allergic to it. It is contraindicated in patients having severe myocardial insufficiency, a recent history of myocardial infarction (MI), severe persistent drug-induced myelosuppression and severe liver disease. Hence avoid using this medicine under such conditions. Inform your doctor if you have any cardiovascular conditions, liver/kidney disease, or taking any CYP3A4 or CYP2D6 inducers medication, as it can cause serious adverse effects. Adriamycin 50 mg Injection is known to cause embryo-fetal toxicity. Hence it is contraindicated in pregnant or breastfeeding women. Do not stop receiving Adriamycin 50 mg Injection without a doctor’s advice, as it can cause serious health conditions. Adriamycin 50 mg Injection is known to cause secondary malignancies, tissue necrosis, cardiomyopathy and septic shock in some patients. Hence careful monitoring of the patient is needed while receiving the medicine.
Therapeutic Class
Drug-Drug Interactions
Drug-Food Interactions
Diet & Lifestyle Advise
Habit Forming
How Adriamycin 50 mg Injection Works
What if I have taken an overdose of Adriamycin 50 mg Injection
Alcohol
Unsafe
Alcohol intake might increase the risk of stomach or intestine bleeding. Alcohol consumption is not recommended.
Pregnancy
Unsafe
Adriamycin 50 mg Injection is not recommended for use in pregnancy as it may harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Adriamycin 50 mg Injection. Use reliable methods of birth control while on treatment with Adriamycin 50 mg Injection.
Breast Feeding
Unsafe
It is not recommended for use in breastfeeding as it may pass into breast milk and harm your infant. Hence, if you are breastfeeding, inform your doctor before receiving Adriamycin 50 mg Injection. Your doctor may suggest you stop feeding while on treatment with this medicine.
Driving
Caution
Adriamycin 50 mg Injection may cause dizziness and tiredness; therefore, avoid driving vehicles or operating machinery until you return to normal.
Liver
Caution
Adriamycin 50 mg Injection should be used with caution in patients with liver impairment. However, this medicine is contraindicated in patients with severe liver disease. If you have a pre-existing or a history of liver disease, inform your doctor. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.
Kidney
Caution
If you have a pre-existing or a history of kidney disease, inform your doctor. Your doctor may adjust the dose or prescribe a suitable alternative, if necessary, based on your condition.
Children
Consult your doctor
Adriamycin 50 mg Injection is used to treat neuroblastoma (cancer that starts in nerve cells and primarily affects children) and Wilms' tumor (a form of kidney cancer that affects children). Your doctor may recommend a suitable dosage based on your child's condition.
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