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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 23, 2024 | 4:50 PM IST
Active B12 PG Tablet is used in the treatment of neuropathic pain. It contains Pregabalin and Methylcobalamin, which decreases the pain signals and helps rejuvenate and protect damaged nerve cells. It may cause common side effects such as dizziness, drowsiness, headache, loss of appetite, nausea or vomiting, diarrhea, headache, vision problems, and sweating. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Wonder Therapeutics Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Active B12 PG Tablet

Active B12 PG Tablet belongs to the class of medications ‘anticonvulsants’ used in the treatment of neuropathic pain. Neuropathic pain is a chronic (long-term) progressive nerve disease that causes nerve pain due to nerve damage or the nervous system's malfunctioning. It is mostly seen in patients who had suffered a trauma or nerve injury, diabetes, vitamin deficiencies, cancer, multiple sclerosis (disease of the brain and spinal cord), shingles (a viral infection), and HIV.

Active B12 PG Tablet is a combination of two medicines: Pregabalin and Methylcobalamin. Pregabalin acts by decreasing the pain signals sent by a damaged nerve in the body. On the other hand, Methylcobalamin helps rejuvenate and protect damaged nerve cells by producing a substance called myelin (outer protective layer of nerve cell - neuron).

You should take this medicine as prescribed by your doctor. The common side-effects of Active B12 PG Tablet are dizziness, drowsiness, headache, anorexia (loss of appetite), nausea or vomiting, diarrhea, headache, hot sensation (burning pain), vision problems, and diaphoresis (sweating). Inform your doctor if any of these side effects persist.

Do not take Active B12 PG Tablet if you are allergic to ‘Pregabalin’ and ‘Methylcobalamin’ or any contents before taking Active B12 PG Tablet if you have a history of heart diseases, liver or kidney disease, alcoholism, or drug abuse.  It should not be used in children and adolescents below 18 years. Inform your doctor if you are pregnant and breastfeeding. Do not drive or operate heavy machinery as Active B12 PG Tablet may cause dizziness or drowsiness. Active B12 PG Tablet contains lactose, so inform your doctor if you have any intolerance to sugars. Do not discontinue treatment without telling your doctor. 

Uses of Active B12 PG Tablet

Treatment of Neuropathic pain.

Medicinal Benefits

Active B12 PG Tablet is a combination of two drugs: Pregabalin and Methylcobalamin. Pregabalin is an anticonvulsant that affects the brain's chemicals that send pain signals across the nervous system. It works by binding to the specific site on voltage-gated calcium channels (responsible for excitatory response), thereby decreasing brain activity. This effect helps in relieving nerve pain and lowers the risk of seizures. On the other hand, Methylcobalamin is a form of vitamin B12 that helps rejuvenate and protect damaged nerve cells by producing a substance called myelin (outer protective layer of nerve cells). Together, Active B12 PG Tablet helps in providing relief from neuropathic pain and improved nerve signal conduction.  

 

Side Effects of Active B12 PG Tablet

  • Dizziness
  • Drowsiness
  • Headache
  • Anorexia (loss of appetite)
  • Nausea or vomiting
  • Diarrhea
  • Headache
  • Sore throat
  • Vision problems
  • Hot sensation (burning pain)
  • Diaphoresis (sweating)
  • Weight gain

Directions for Use

Swallow the medicine as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Active B12 PG Tablet may increase the risk of heart failure in patients with heart diseases. It may cause dizziness and somnolence (sleepiness). So, it might increase the risk of accidental injury in elderly patients. Active B12 PG Tablet may also cause temporary vision problems. However, if this condition is persistent, consult your doctor immediately. Patients with diabetes who gain weight with Active B12 PG Tablet may need a change in diabetic medicines. If you notice decreased urination while taking Active B12 PG Tablet , inform your doctor as Active B12 PG Tablet may cause kidney failure in some cases. It may increase suicidal tendencies, though it is rare. You may experience convulsions after discontinuing Active B12 PG Tablet . In such cases, inform your doctor immediately.  

Therapeutic Class

ANTICONVULSANT

Diet & Lifestyle Advise

  • Include food rich in vitamin B and D in your diet.

  • Include cayenne pepper in your diet as it can help in lowering neuropathic pain.

  • Exercising regularly helps in improving overall health and combating pain.

  • Rest well, get plenty of sleep.

  • Try taking a warm bath as it can be soothing.

  • Avoid smoking and alcohol consumption.

  • Meditation and yoga can help lower stress, decrease pain sensitivity, and improves coping skills.

  • Acupuncture can be helpful by stimulating pressure points.

  • Using essential oils for massages can help increase circulation.

 

Habit Forming

Yes

What if I have taken an overdose of Active B12 PG Tablet

Do not take more than the prescribed dose of Active B12 PG Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Country of origin

India

Manufacturer/Marketer address

Head Office: A2/494, Sec-8, Rohini Delhi - 110085
Other Info - ACT0522

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