Acoxim-500 Tablet belongs to the class of antibiotics known as cephalosporin, indicated for treating a wide range of bacterial infections. It helps in the treatment of urinary tract infections (UTI), Mild to moderate lower respiratory tract infections (bronchitis), severe lower respiratory tract infections (pneumonia), pyelonephritis (kidney inflammation due to the bacterial infection), uncomplicated gonorrhoea (sexually transmitted infection), Lyme disease (caused due to biting of infected black-legged tick insect) in adults and children above 12 years of age.

Acoxim-500 Tablet is a broad-spectrum antibiotic that kills a wide range of bacteria (bactericidal). It kills the bacterial cell by binding to the outer layer of the bacteria and blocking the activity of the enzyme that makes peptidoglycan (a vital component of the bacterial cell wall). As a result, the bacterial cell cannot grow and multiply and finally gets killed.

You should take Acoxim-500 Tablet only if your doctor has prescribed you. Acoxim-500 Tablet is available in various forms, such as oral tablets, dispersible tablets, and oral suspension. Most bacterial infections get treated within one week, while some conditions might take longer. So, it would be best if you tried to complete the dose your doctor prescribed for the specific bacterial infection. During the treatment with Acoxim-500 Tablet, you may observe some mild and transient nature of common side effects like headache, dizziness,  stomach upset, overgrowth of candida (fungal skin infection), unpleasant taste in the mouth, diaper rashes, and eosinophilia (increased disease-fighting cells WBCs). These side effects are usually in the initial phase and then resolved after some time. However, if these side effects persist, let your doctor know about them.

Overdosage of Acoxim-500 Tablet can cause brain problems (cerebral irritation with fits or convulsions attack). There is no clinical evidence of a Acoxim-500 Tablet effect on the mother or baby during pregnancy. However, one should take the Acoxim-500 Tablet with caution. Acoxim-500 Tablet is excreted in the breastmilk, so the nursing mother should cautiously take Acoxim-500 Tablet. This antibiotic may cause dizziness, so patients should be cautious while driving a motor vehicle or operating machinery. Acoxim-500 Tablet is not recommended for people allergic or hypersensitive to Acoxim-500 Tablet, penicillin, or other beta-lactam antibiotics. In the initial stage of the treatment, you might have diarrhoea and abdominal cramps due to loss of gut flora (good intestinal/gut bacteria that aids digestion). So, the doctor may prescribe you prebiotics or probiotics to increase the number of gut flora. You can drink alcoholic beverages while taking amoxicillin, as it does not interact with Acoxim-500 Tablet. Liver and kidney-affected people should take this medication with caution.

Acoxim-500 Tablet treats a wide range of bacterial infections caused due to gram-positive and gram-negative bacteria. It helps treat respiratory tract infections, ear infections, skin infections, genitourinary infections, and bone infections. Besides this, Acoxim-500 Tablet also prevents in spreading of the infection after surgery and in the early treatment of Lyme disease caused by bacteria (Borrelia burgdorferi) in adults and children over the age of 12 years. The usual course of Acoxim-500 Tablet is seven days (5-10 days). But, your doctor might prescribe you Acoxim-500 Tablet for a longer duration depending on the condition of infection. Acoxim-500 Tablet has excellent antibacterial activity against gram-positive and gram-negative bacteria, including Staphylococcus aureus, Haemophilus para influenza, Streptococcus pneumonia, S. pyrogens, Haemophilus influenzae, Klebsiella pneumoniae, Moraxella catarrhalis, and Neisseria gonorrhoeae.

• Headache

• Dizziness
• Stomach upset
• Overgrowth of candida (fungal skin infection)
• Unpleasant taste in the mouth
• Diaper rashes
• Eosinophilia (increased disease-fighting cells/WBC) 

Special care should be taken by the people taking Acoxim-500 Tablet who have allergic reactions to penicillin or other beta-lactam antibiotics. Use with other antibiotics may lead to a fungal skin infection known as Candida. Prolonged use of Acoxim-500 Tablet may also cause an overgrowth of other pathogens (like enterococci and Clostridium difficile), which can be prevented by stopping Acoxim-500 Tablet. The case of colitis (inflammatory bowel disease) has been reported using Acoxim-500 Tablet. Hence, it is important to consider the proper diagnosis of the patients who developed diarrhoea after taking Acoxim-500 Tablet. If the symptom of diarrhoea persists for a longer duration, the patient may experience abdominal cramps. In this situation, you should discontinue the intake of Acoxim-500 Tablet immediately. The Jarisch-Herxheimer reaction (caused due to toxins released by the death of bacteria within the body during antibiotic treatment) has been seen in the patients taking Acoxim-500 Tablet for the treatment of Lyme disease. Your ability to perform tasks that require judgment, cognitive, or body movement may be affected, and you may have dizziness. So patients taking Acoxim-500 Tablet should be warned to be cautious when driving or operating machinery.

Drug-Drug Interactions: You should avoid taking Acoxim-500 Tablet with oral birth control pills, medicines that reduce gastric acidity (like antacids, omeprazole), immuno-suppressing drugs (mycophenolate or mycophenolic acid), medicines used for reducing uric acid (probenecid), and some urine glucose tests. Besides this, it also interacts with typhoid and BCG vaccines.

Drug-Food Interactions: Grapefruit juice and dietary supplements containing minerals like calcium may also work to dampen the effect of antibiotics.

Drug-Disease Interactions: Acoxim-500 Tablet should not be given in the condition of colitis, kidney disease, patient planning for ferricyanide tests, patient on dialysis, liver disease, epilepsy (fits) and diarrhoea.

• OMEPRAZOLE
• PROBENECID
• MYCOPHENOLIC ACID

• It would be best to take probiotics after taking the full course of Acoxim-500 Tablet to restore some of the healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.

• Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria which helps stimulate their growth. Thus fibre foods may help restore healthy gut bacteria after taking a course of antibiotics. Whole grains like whole-grain bread, and brown rice, should be included in your diet.

• Avoid taking too much calcium enriched foods and drinks as it might affect the working of Acoxim-500 Tablet.

• Avoid intake of alcoholic beverages with Acoxim-500 Tablet as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the Acoxim-500 Tablet in fighting off infections.

A bacterial infection is a condition in which harmful bacteria enter, multiply and infect our body. It can target any body part and multiple very quickly. When you get infected with bacteria, you can experience generalized symptoms like fevers, chills, and fatigue. Bacteria are of various forms comprising commonly spherical, rod, and spiral-shaped. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. Few harmful bacteria that cause infections include Streptococcus, Staphylococcus, and E. coli. Anyone can become infected with a bacterial infection. But, people with weak immune systems or taking immunosuppressive medicine can make you more prone to bacterial infection.