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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 10, 2024 | 7:20 PM IST
Aceno 4Mg Tablet is used to prevent and treat various types of thromboembolic diseases (blood clots inside blood vessels), including deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung). It is prescribed to prevent formation of unwanted clots if you have a condition that increases this risk, such as atrial fibrillation, or if you have had a heart valve replacement. It is also given to prevent any clots that may have already formed in the blood vessels of your legs, lungs or heart from becoming larger and causing problems. It works by increasing the time it takes for your blood to clot, reducing the risk of a stroke or heart attack. This medication helps to keep blood flowing smoothly in your body by decreasing the amount/number of clotting proteins in the blood. Some people may experience unusual bleeding or skin rash.
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Prescription drug

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Prescription drug
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Manufacturer/Marketer

Zydus Healthcare Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Aceno 4Mg Tablet

Aceno 4Mg Tablet is used to prevent and treat various types of thromboembolic diseases (blood clots inside blood vessels), including deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung). Deep vein thrombosis is a medical condition in which blood clots form in deep veins, usually in the legs. Pulmonary embolism is a condition in which a blood clot blocks the arteries in the lungs.

Aceno 4Mg Tablet is prescribed to prevent unwanted clots from forming if you have a condition that puts you at risk of this happening, such as atrial fibrillation, or if you have had a heart valve replacement. It is also given to prevent any clots that may have already formed in the blood vessels of your legs, lungs or heart from becoming larger and causing problems. Aceno 4Mg Tablet works by increasing the time it takes for your blood to clot, reducing the risk of a stroke or heart attack. This medication helps to keep blood flowing smoothly in your body by decreasing the amount/number of clotting proteins in the blood. Aceno 4Mg Tablet does not dissolve blood clots that have already formed but may stop them from becoming larger and causing more serious problems.

Take Aceno 4Mg Tablet , preferably with or without food, and swallow whole with a glass of water. Do not crush, chew or break it. Your doctor will advise you on how often you take your tablets based on your medical condition. Some people may experience unusual bleeding or skin rash. Most of these side effects of Aceno 4Mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Aceno 4Mg Tablet or any other medicines, please tell your doctor. If you are pregnant, trying for a baby or breastfeeding, it is advised to consult a doctor before using Aceno 4Mg Tablet . If you have any cuts or wounds, stomach ulcers, kidney or liver problems, high blood pressure or bleeding problems or if you are taking or using any other medicines. This includes any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines.  Inform your doctor before taking Aceno 4Mg Tablet . It would help if you had frequent 'INR' (international normalized ratio) or prothrombin time tests to measure your blood clotting time, as Aceno 4Mg Tablet prolongs bleeding time. You must be cautious while shaving and brushing your teeth to avoid too much bleeding from the injury site.

Uses of Aceno 4Mg Tablet

Prevent and treat harmful blood clots, Reducing the risk of a stroke or heart attack.

Medicinal Benefits

Aceno 4Mg Tablet  is the popular drug of choice for oral anticoagulant therapy in many indications like calf deep vein thrombosis (blood clots in leg veins), proximal deep vein thrombosis (blood clots in a deep vein), pulmonary embolism (A condition in which one or more arteries in the lungs become blocked by a blood clot), recurrent venous thromboembolism (a blood clot forms most often in the deep veins of the leg, groin or arm), cardioversion, atrial fibrillation (An irregular, often rapid heart rate that commonly causes poor blood flow), antiphospholipid syndrome (A disorder in which the immune system mistakenly attacks normal proteins in the blood) and mechanical heart valves. Aceno 4Mg Tablet works by inhibiting the production of clotting factors by decreasing the action of vitamin K. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clot formation.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Aceno 4Mg Tablet

  • Unusual bleeding from the gums
  • Heavy bleeding from cuts or wounds
  • Unexplained bruising or nosebleeds
  • Heavy periods
  • Abdominal pain
  • Blood vomiting
  • Bloody or black tarry stools
  • Blood in the urine
  • Backache
  • Dizziness
  • Severe headache
  • Weakness in an arm or leg
  • Blurred vision
  • A blood clot in the eye (visible pool of blood)

Drug Warnings

Indigestion medicines known as proton pump inhibitors like omeprazole should be used with caution while taking Aceno 4Mg Tablet . Prolonged use of Aceno 4Mg Tablet can cause bleeding problems (like nosebleeds, heavier periods, bleeding gums, and easy bruising). If you are going to have any surgery, discontinue taking Aceno 4Mg Tablet five days before the surgery. Discontinuation of Aceno 4Mg Tablet might increase the risk of heart attack, stroke, and other risks of cardiovascular events. So, do not stop taking Aceno 4Mg Tablet of a sudden on your own decision. If you have had any recent stroke or heart attack, stop the intake of Aceno 4Mg Tablet with painkillers like aspirin or ibuprofen as it can increase your stomach or gastrointestinal bleeding. Purpura (blood leakage under the skin) has been observed using Aceno 4Mg Tablet , including fatal cases. If you are pregnant, planning for pregnancy, or are a nursing mother, tell your doctor that you are taking Aceno 4Mg Tablet .

Drug Interactions

Drug-Drug Interactions: Aceno 4Mg Tablet may have interaction with other anticoagulants (e.g. heparin, dipyridamole, clopidogrel, ticlopidine), anti-arrhythmic agents (e.g. amiodarone, quinidine), antibiotics (e.g. clindamycin). medicine used against pain (e.g. diacetylsalicylic acid, aminosalicylic acid, diflunisal), an antidepressant (e.g. citalopram), HIV protease inhibitors (e.g. ritonavir, nelfinavir), protease inhibitors (e.g. indinavir, nelfinavir, ritonavir, saquinavir), barbiturates (e.g. Phenobarbital), antacids (e.g. magnesium hydroxide), and proton pump inhibitors (e.g. omeprazole).

Drug-Food Interactions: You should avoid drinking cranberry juice or taking other cranberry products and also Aceno 4Mg Tablet may interact with herbs and supplements including include garlic, ginger, bilberry, danshen, piracetam, ginkgo biloba and St John’s wort plant (used as an antidepressant) and increase the risk of bleeding.

Drug-Disease Interactions: Aceno 4Mg Tablet should not be given to the people with stomach ulcers, brain haemorrhage (bleeding in your brain), haemophilia (a bleeding disorder), and liver or kidney problems.

Drug-Drug Interactions Checker List

  • HEPARIN
  • CLINDAMYCIN
  • CLOPIDOGREL
  • CELECOXIB
  • METHYLPREDNISOLONE
  • ACETYLSALICYLIC ACID
  • DIPYRIDAMOLE
  • TICLOPIDINE

Habit Forming

No

Diet & Lifestyle Advise

  • A low cholesterol diet and a regular exercise regime complement treatment with Aceno 4Mg Tablet effectively.

  • As a precautionary measure, you are recommended not to consume alcohol, or junk food items from outside, stick to a freshly prepared home-cooked meal and rest properly for a speedy recovery.

  • And also, try to replace most of your saturated fats with unsaturated fats to reduce total cholesterol and LDL in a short time.

  • Foods like avocados, olive oil, fatty fish and nuts contain many heart-healthy unsaturated fats, so eating them regularly is beneficial.

  • Option for foods that are high in vitamin K (liver, leafy green vegetables, or vegetable oils) as Aceno 4Mg Tablet may lower Vitamin K in your body.

  • Avoid drinking alcohol as it increases the risk of gastrointestinal ulcer/bleeding.

  • Cranberry juice, grapefruit juice, noni juice, and pomegranate juice may interact with Aceno 4Mg Tablet and lead to unwanted side effects. Hence try to avoid these juices while taking Aceno 4Mg Tablet .

Special Advise

  • Caution and more frequent monitoring of platelet count, factor V assay, fibrinogen level test, prothrombin time test (PT or PT-INR) and the INR, or international normalised ratio to analyze your blood clotting time.

  • You should NOT receive injections into your muscles whilst taking Aceno 4Mg Tablet . If you need any injections into your spine or as part of a scan or X-ray test, or if you need minor surgery, including dental surgery, make sure you discuss your treatment with your doctor first.

Disease/Condition Glossary

Blood clots can occur in any body part, leading to a heart attack, stroke, and organ damage (even coma or death). Blood clots can reach your arteries or veins in organs like the brain, kidney, heart, lungs, and limbs. Conditions like atherosclerosis, diabetes, heart failure, irregular heartbeat (arrhythmia), and obesity/overweight can trigger excessive blood clotting in the brain and heart. On the other hand, deep vein thrombosis (blood clot in veins), peripheral artery disease (narrowed arteries due to fat deposit or blood clot), and atherosclerosis (fat built upon the walls of the arteries) can cause a blood clot in your limbs.

Deep vein thrombosis (blood clots in the legs) is a medical condition in which blood clots form in deep veins, usually in the legs. The symptoms include leg pain or swelling. 

Pulmonary embolism (blood clots in the lung) is a chronic condition which occurs as the blood clots break and travel to the lungs from deep veins in the legs or other parts of the body. The symptoms of pulmonary embolism include cough, chest pain, and shortness of breath.

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Alcohol

Caution

You are recommended to avoid the consumption of alcohol with Aceno 4Mg Tablet as it may increase the risk of bleeding.

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Pregnancy

Unsafe

Aceno 4Mg Tablet is recommended not to use in pregnancy. Your doctor will discuss with you the potential risk of taking Aceno 4Mg Tablet during pregnancy. Please consult your doctor.

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Breast Feeding

Caution

Aceno 4Mg Tablet should not be taken until prescribed. Your doctor will weigh the benefits and potential risks before prescribing them. Please consult your doctor. You and your child may require blood tests if you are breastfeeding while taking Aceno 4Mg Tablet . However, as a precaution, your doctor may prescribe vitamin K to your child to prevent their blood from thinning.

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Driving

Safe if prescribed

Aceno 4Mg Tablet has no or negligible influence on the ability to drive or use machines.

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Liver

Caution

Take the Aceno 4Mg Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take the Aceno 4Mg Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Aceno 4Mg Tablet should not be taken until prescribed. Your doctor will weigh the benefits and potential risks before prescribing them. If Aceno 4Mg Tablet is used in children or adolescents, blood should be tested more often to see how well the medicine works.

Country of origin

India

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.
Other Info - ACE0671

Author Details

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FAQs

Aceno 4Mg Tablet is used to prevent and treat harmful blood clots, Reducing the risk of a stroke or heart attack.
Aceno 4Mg Tablet works by increasing the time it takes for your blood to clot, reducing the risk of a stroke or heart attack. This medication helps to keep blood flowing smoothly in your body by decreasing the amount/number of clotting proteins in the blood.
Yes, Aceno 4Mg Tablet causes blood thinning. It works by preventing platelets (a type of blood cells) from sticking together and forming clots.
Please consult your doctor if Aceno 4Mg Tablet needs to be stopped before undergoing surgery. The doctor might ask you to stop taking Aceno 4Mg Tablet a few days before surgery to avoid the increased risk of bleeding during the procedure.
Do not take aspirin for pain relief or ibuprofen while you are taking Aceno 4Mg Tablet unless your doctor says it's OK. They raise the risk of unusual bleeding.
When a blood clot is treated, guidelines recommend that patients take blood thinners for the rest of its life. If they do not, the chance of developing a second clot is 30 to 40 per cent in the next 10 years.
There might be a problem if you are taking herbal therapies with Aceno 4Mg Tablet , especially that affects blood like Ginkgo Biloba and St John's wort plant extract used as an antidepressant. Together with taking can increase your risk of bleeding. Tell your doctor if you are using any type of herbal supplements before taking Aceno 4Mg Tablet .
No, you are usually not advised to have a tattoo or body piercing while taking Aceno 4Mg Tablet as it may increase the risk of bleeding and infection. If you still wish to proceed further, contact your doctor so that the dose may be adjusted or any antibiotics may be prescribed and let the piercer or tattooist know in advance that you are on treatment with a blood thinner.
No, you are not recommended to stop taking Aceno 4Mg Tablet without consulting your doctor as it may worsen the condition. Therefore, take Aceno 4Mg Tablet for as long as your doctor has prescribed it.
You can have platelet count, factor V assay, fibrinogen level test, prothrombin time test (PT or PT-INR) and the INR, or international normalised ratio to analyze your blood clotting time.
Yes, taking Aceno 4Mg Tablet can increase the risk of bleeding as it contains aspirin which is a blood thinner. So, please be very cautious while shaving, cutting fingernails or toenails, or using sharp objects to avoid any bleeding.
Aceno 4Mg Tablet may cause side effects like unusual bleeding or skin rash. Most of these side effects of Aceno 4Mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Aceno 4Mg Tablet can be taken with or without food or as advised by the doctor.

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